Detailed information NTG0800288

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: P1X13_RS04335
• Genome accession: NZ_CP119678
• Coordinates: 875039..875875 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1004
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 870039..880875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1X13_RS04305 (P1X13_04305)	-	870593..870961 (+)	369	WP_010922310.1	hypothetical protein	-
P1X13_RS04310 (P1X13_04310)	-	871011..871922 (-)	912	WP_136273951.1	diacylglycerol kinase family protein	-
P1X13_RS04315 (P1X13_04315)	-	872039..872689 (-)	651	WP_002984629.1	hemolysin III family protein	-
P1X13_RS04320 (P1X13_04320)	-	872686..873126 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
P1X13_RS04325 (P1X13_04325)	ylqF	873345..874193 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
P1X13_RS04330 (P1X13_04330)	-	874183..874974 (+)	792	WP_011285534.1	ribonuclease HII	-
P1X13_RS04335 (P1X13_04335)	dprA	875039..875875 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
P1X13_RS04340 (P1X13_04340)	topA	875982..878111 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
P1X13_RS04345 (P1X13_04345)	-	878186..879068 (-)	883	Protein_808	LysR family transcriptional regulator	-
P1X13_RS04350 (P1X13_04350)	-	879081..879626 (+)	546	Protein_809	PTS sugar transporter subunit IIC	-
P1X13_RS04355 (P1X13_04355)	-	879641..880633 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=800288 P1X13_RS04335 WP_010922314.1 875039..875875(+) (dprA) [Streptococcus pyogenes strain 1004]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=800288 P1X13_RS04335 WP_010922314.1 875039..875875(+) (dprA) [Streptococcus pyogenes strain 1004]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367