Detailed information NTG0800039

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: P1Y72_RS01690
• Genome accession: NZ_CP119599
• Coordinates: 357188..358024 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1133
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 352188..363024

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1Y72_RS01660 (P1Y72_01660)	-	352742..353110 (+)	369	WP_010922310.1	hypothetical protein	-
P1Y72_RS01665 (P1Y72_01665)	-	353160..354071 (-)	912	WP_136273951.1	diacylglycerol kinase family protein	-
P1Y72_RS01670 (P1Y72_01670)	-	354188..354838 (-)	651	WP_002984629.1	hemolysin III family protein	-
P1Y72_RS01675 (P1Y72_01675)	-	354835..355275 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
P1Y72_RS01680 (P1Y72_01680)	ylqF	355494..356342 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
P1Y72_RS01685 (P1Y72_01685)	-	356332..357123 (+)	792	WP_011285534.1	ribonuclease HII	-
P1Y72_RS01690 (P1Y72_01690)	dprA	357188..358024 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
P1Y72_RS01695 (P1Y72_01695)	topA	358131..360260 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
P1Y72_RS01700 (P1Y72_01700)	-	360335..361217 (-)	883	Protein_335	LysR family transcriptional regulator	-
P1Y72_RS01705 (P1Y72_01705)	-	361230..361775 (+)	546	Protein_336	PTS sugar transporter subunit IIC	-
P1Y72_RS01710 (P1Y72_01710)	-	361790..362782 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=800039 P1Y72_RS01690 WP_010922314.1 357188..358024(+) (dprA) [Streptococcus pyogenes strain 1133]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=800039 P1Y72_RS01690 WP_010922314.1 357188..358024(+) (dprA) [Streptococcus pyogenes strain 1133]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367