Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   P1T45_RS06245 Genome accession   NZ_CP119427
Coordinates   1157325..1157999 (-) Length   224 a.a.
NCBI ID   WP_003104260.1    Uniprot ID   A0A0E2UA77
Organism   Streptococcus parauberis strain KSP45     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1152325..1162999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1T45_RS06220 (P1T45_06225) - 1152603..1153880 (-) 1278 WP_003102832.1 pyrimidine-nucleoside phosphorylase -
  P1T45_RS06225 (P1T45_06230) - 1153867..1154466 (-) 600 WP_003103028.1 class I SAM-dependent methyltransferase -
  P1T45_RS06230 (P1T45_06235) coaA 1154717..1155637 (+) 921 WP_003108420.1 type I pantothenate kinase -
  P1T45_RS06235 (P1T45_06240) rpsT 1155706..1155939 (+) 234 WP_003105398.1 30S ribosomal protein S20 -
  P1T45_RS06240 (P1T45_06245) - 1156029..1157332 (-) 1304 Protein_1185 sensor histidine kinase -
  P1T45_RS06245 (P1T45_06250) ciaR 1157325..1157999 (-) 675 WP_003104260.1 response regulator transcription factor Regulator
  P1T45_RS06250 (P1T45_06255) - 1158084..1160654 (-) 2571 WP_308695312.1 M1 family metallopeptidase -
  P1T45_RS06255 (P1T45_06260) phoU 1160718..1161371 (-) 654 WP_003103398.1 phosphate signaling complex protein PhoU -
  P1T45_RS06260 (P1T45_06265) pstB 1161437..1162183 (-) 747 WP_308695766.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25767.68 Da        Isoelectric Point: 4.3994

>NTDB_id=799255 P1T45_RS06245 WP_003104260.1 1157325..1157999(-) (ciaR) [Streptococcus parauberis strain KSP45]
MIKILLVEDDLSLSNSIFDFLDDFADVLQVFDGDEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKDIHTAVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLMDSSLYYKNLKVDTERNVVTVDEKEVELLGKEFELLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTKFVADLQTLRSVGYILKTNE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=799255 P1T45_RS06245 WP_003104260.1 1157325..1157999(-) (ciaR) [Streptococcus parauberis strain KSP45]
ATGATAAAAATATTATTAGTCGAAGATGATTTGAGTTTGTCCAATTCAATATTTGATTTTTTAGATGACTTTGCTGATGT
CTTACAAGTTTTTGATGGTGATGAGGGGCTTTATGAGGCTGAAAGTGGTGTCTATGACTTAATTTTGCTTGATTTAATGC
TTCCAGAAAAAGATGGTTTTCAAGTTTTAAAAGAGCTTAGGGAAAAAGATATTCATACAGCTGTGTTAATCATGACCGCT
AAAGAGAGTCTTGATGATAAAGGTCATGGTTTTGAATTAGGAGCTGATGATTATTTAACTAAGCCGTTTTATCTTGAAGA
ATTGAAGATGCGCATCCAAGCATTACTCAAACGTTCTGGCAAGCTGATGGACAGTAGTCTATATTATAAAAATCTAAAAG
TTGATACAGAACGTAATGTCGTTACTGTTGATGAGAAGGAAGTGGAATTACTTGGAAAAGAGTTTGAATTACTTGTTTAT
TTCCTTCAAAATCAAAACGTTATTTTGCCAAAATCACAGATATTTGATCGAATTTGGGGATTTGATAGTGATACAACAAT
TTCAGTCGTAGAAGTTTATGTTTCAAAAATACGAAAAAAATTGAAGGGAACAAAATTTGTTGCTGATTTACAAACTCTTC
GGAGCGTTGGCTACATTTTAAAAACAAATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UA77

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae Rx1

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae D39

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae R6

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae TIGR4

83.71

98.661

0.826
  vicR Streptococcus mutans UA159

35.745

100

0.375
  micA Streptococcus pneumoniae Cp1015

35.47

100

0.371
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.444

100

0.366