NTDB

Overview

Name	vicR	Type	Regulator
Locus tag	P1T45_RS03405	Genome accession	NZ_CP119427
Coordinates	598501..599211 (+)	Length	236 a.a.
NCBI ID	WP_003102576.1	Uniprot ID	A0A1S1ZPR9
Organism	Streptococcus parauberis strain KSP45
Function	repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 593501..604211

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1T45_RS03380 (P1T45_03385)	-	594236..595258 (+)	1023	WP_003105201.1	DUF3114 domain-containing protein	-
P1T45_RS03385 (P1T45_03390)	-	595266..595913 (-)	648	WP_003104005.1	amino acid ABC transporter permease	-
P1T45_RS03390 (P1T45_03395)	-	595928..596632 (-)	705	WP_003104614.1	amino acid ABC transporter permease	-
P1T45_RS03395 (P1T45_03400)	-	596646..597461 (-)	816	WP_003106354.1	transporter substrate-binding domain-containing protein	-
P1T45_RS03400 (P1T45_03405)	-	597474..598253 (-)	780	WP_003106355.1	amino acid ABC transporter ATP-binding protein	-
P1T45_RS03405 (P1T45_03410)	vicR	598501..599211 (+)	711	WP_003102576.1	response regulator YycF	Regulator
P1T45_RS03410 (P1T45_03415)	vicK	599204..600564 (+)	1361	Protein_621	cell wall metabolism sensor histidine kinase VicK	-
P1T45_RS03415 (P1T45_03420)	vicX	600569..601378 (+)	810	WP_037619792.1	MBL fold metallo-hydrolase	Regulator
P1T45_RS03420 (P1T45_03425)	rnc	601476..602168 (+)	693	WP_003103277.1	ribonuclease III	-

Sequence

Protein

Download Length: 236 a.a. Molecular weight: 26995.82 Da Isoelectric Point: 4.9038

                                >NTDB_id=799245 P1T45_RS03405 WP_003102576.1 598501..599211(+) (vicR) [Streptococcus parauberis strain KSP45]

MKKVLIVDDEKPISDIIKFNLTKEGYDTITAFDGREAVTAFEEEKPDLVILDLMLPELDGLEVAKEIRKTSHIPIIMLSA

KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENAISGTQELTIGNLQILPDAFVAKKYGNEVE

LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKAHD

Nucleotide

Download Length: 711 bp

                                >NTDB_id=799245 P1T45_RS03405 WP_003102576.1 598501..599211(+) (vicR) [Streptococcus parauberis strain KSP45]

ATGAAAAAAGTTCTGATTGTCGATGATGAAAAGCCAATTTCAGATATCATCAAATTCAATTTAACAAAAGAAGGGTATGA

TACAATTACTGCCTTTGATGGGCGTGAAGCTGTAACTGCTTTTGAAGAAGAAAAACCTGACTTAGTTATTCTCGACTTAA

TGCTTCCTGAGTTGGATGGTCTTGAAGTAGCTAAGGAAATTCGCAAAACAAGTCATATCCCTATTATTATGCTTTCTGCT

AAAGATAGTGAATTTGATAAAGTTATTGGGCTTGAAATCGGTGCAGATGACTATGTGACCAAACCTTTTTCAAATCGTGA

ATTATTAGCCCGTGTAAAAGCTCATTTACGAAGAACTGAGACGATTGAAACAGCAGTCGCAGAGGAAAATGCTATCTCTG

GTACACAAGAATTAACTATCGGAAATTTACAAATTCTTCCGGATGCCTTTGTTGCCAAAAAATATGGTAATGAAGTTGAG

CTTACCCATCGTGAATTTGAATTGTTGCATCATTTAGCAAATCACATTGGTCAAGTTATGACTCGTGAGCACCTGCTTGA

AACGGTTTGGGGTTATGATTATTTTGGCGATGTTCGAACTGTCGATGTAACTGTTCGTCGTTTGAGAGAAAAAATTGAAG

ATACGCCTAGCCGTCCTGAATACATTTTGACAAGACGTGGTGTTGGCTATTATATGAAGGCGCATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A1S1ZPR9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
vicR	Streptococcus mutans UA159	89.407	100	0.894
micA	Streptococcus pneumoniae Cp1015	77.872	99.576	0.775
covR	Streptococcus salivarius strain HSISS4	43.348	98.729	0.428
covR	Lactococcus lactis subsp. lactis strain DGCC12653	43.103	98.305	0.424
scnR	Streptococcus mutans UA159	36.975	100	0.373

Detailed information NTG0799245