Detailed information NTG0798050

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PY824_RS05575
• Genome accession: NZ_CP119172
• Coordinates: 1030955..1031797 (-)
• Length: 280 a.a.
• NCBI ID: WP_039670791.1
• Uniprot ID: A0A380K8L7
• Organism: Streptococcus macedonicus strain SGM CIP105683
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1025955..1036797

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PY824_RS05560 (PY824_05560)	-	1027214..1027934 (-)	721	Protein_1026	DUF3307 domain-containing protein	-
PY824_RS05565 (PY824_05565)	-	1027934..1028601 (-)	668	Protein_1027	SatD family protein	-
PY824_RS05570 (PY824_05570)	topA	1028719..1030860 (-)	2142	WP_014294544.1	type I DNA topoisomerase	-
PY824_RS05575 (PY824_05575)	dprA	1030955..1031797 (-)	843	WP_039670791.1	DNA-processing protein DprA	Machinery gene
PY824_RS05580 (PY824_05580)	-	1031871..1032422 (-)	552	WP_039670792.1	sugar O-acetyltransferase	-
PY824_RS05585 (PY824_05585)	-	1032424..1033203 (-)	780	WP_039670793.1	ribonuclease HII	-
PY824_RS05590 (PY824_05590)	ylqF	1033190..1034044 (-)	855	WP_039670794.1	ribosome biogenesis GTPase YlqF	-
PY824_RS05595 (PY824_05595)	-	1034288..1034698 (+)	411	WP_039670795.1	DUF4231 domain-containing protein	-
PY824_RS05600 (PY824_05600)	-	1034892..1035209 (-)	318	WP_039670796.1	hypothetical protein	-
PY824_RS05605 (PY824_05605)	-	1035333..1035548 (+)	216	WP_158526996.1	hypothetical protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31060.12 Da
• Isoelectric Point: 8.6600

>NTDB_id=798050 PY824_RS05575 WP_039670791.1 1030955..1031797(-) (dprA) [Streptococcus macedonicus strain SGM CIP105683]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDTKELHKEFNRFPNISILDGEYP
LELKYCYNPPVLLFYQGNLELLNRSKMAVVGARTASTTGTKSVQKIIKELGNHFVIVSGLARGIDTSAHLSALKNGGASI
AVIGCGLDVYYPKENKQLQEYMAKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVISGLDILSEYQI

Nucleotide

• Length: 843 bp

>NTDB_id=798050 PY824_RS05575 WP_039670791.1 1030955..1031797(-) (dprA) [Streptococcus macedonicus strain SGM CIP105683]
ATGAATAATTTTGAACTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAATATTTTAGCTATTTTGGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTGGACACCAAAGAATTGCACAAAGAATTTAATCGTTTTCCTAATATTTCCATACTAGATGGCGAATACCCA
TTAGAGCTCAAATATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAGTTACTCAATCGCTCCAAAAT
GGCGGTGGTAGGAGCGCGAACAGCCTCAACAACAGGAACTAAATCTGTACAGAAAATCATCAAAGAACTCGGAAATCATT
TTGTTATTGTTAGCGGCCTGGCACGTGGCATTGATACCAGTGCGCATTTATCAGCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGCGGACTGGACGTTTATTATCCCAAAGAAAACAAGCAGTTGCAGGAGTACATGGCTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGTTTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGCGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGAAAATCTGATGGCTGTCATCATTTGATAAAAGAAGGCGCAAAATG
CGTCATATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

3D structure

• AlphaFold DB: A0A380K8L7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	73.741	99.286	0.732
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis SK321	63.214	100	0.632
dprA	Lactococcus lactis subsp. cremoris KW2	60.791	99.286	0.604
dprA	Haemophilus influenzae Rd KW20	38.636	94.286	0.364