Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   PY824_RS02590 Genome accession   NZ_CP119172
Coordinates   463728..464390 (+) Length   220 a.a.
NCBI ID   WP_014294078.1    Uniprot ID   A0A380K6H1
Organism   Streptococcus macedonicus strain SGM CIP105683     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 458728..469390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY824_RS02565 (PY824_02565) - 458772..460172 (+) 1401 WP_115265993.1 Cof-type HAD-IIB family hydrolase -
  PY824_RS02570 (PY824_02570) - 460172..460528 (+) 357 WP_014294074.1 S1 RNA-binding domain-containing protein -
  PY824_RS02575 (PY824_02575) cysK 460648..461577 (-) 930 WP_014294075.1 cysteine synthase A -
  PY824_RS02580 (PY824_02580) - 461681..462373 (-) 693 WP_115265994.1 YigZ family protein -
  PY824_RS02585 (PY824_02585) comFA/cflA 462430..463731 (+) 1302 WP_115265995.1 DEAD/DEAH box helicase Machinery gene
  PY824_RS02590 (PY824_02590) comFC/cflB 463728..464390 (+) 663 WP_014294078.1 ComF family protein Machinery gene
  PY824_RS02595 (PY824_02595) raiA 464466..465014 (+) 549 WP_014294079.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25869.06 Da        Isoelectric Point: 9.2880

>NTDB_id=798040 PY824_RS02590 WP_014294078.1 463728..464390(+) (comFC/cflB) [Streptococcus macedonicus strain SGM CIP105683]
MICLLCEQEFSKKEQFLNLILMKKDDNGVCLECQKTFERIGDIHCPNCYRNGFAQQCLDCQSWEKKHHHVFHEALFTYNS
SMKDYFSKYKFQGDILLSHVFSKEIKQALKKYKNYTVVPVPISPKRLKERQFNQVTALLQAAKISYEDLLIKIEIRKQSD
KTRKERLETLNPFSFKNISKVPENILIIDDIYTTGATLKGIYQLFYENGAKNVKSFTIVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=798040 PY824_RS02590 WP_014294078.1 463728..464390(+) (comFC/cflB) [Streptococcus macedonicus strain SGM CIP105683]
ATGATTTGCCTGCTCTGCGAACAAGAATTTTCCAAAAAAGAACAATTTTTAAACCTTATCTTAATGAAAAAAGATGACAA
CGGCGTGTGTCTGGAGTGTCAAAAAACATTTGAAAGAATAGGAGACATTCATTGCCCAAACTGTTACCGCAACGGCTTTG
CTCAGCAATGCTTAGATTGTCAATCATGGGAAAAAAAGCATCACCATGTGTTTCATGAAGCACTTTTTACTTACAACTCT
TCAATGAAAGACTATTTTTCAAAATATAAATTTCAAGGAGATATTCTTTTAAGTCACGTTTTTTCAAAGGAAATCAAACA
AGCATTAAAAAAATATAAAAACTACACCGTTGTTCCAGTTCCCATAAGTCCAAAACGGCTAAAAGAAAGACAATTTAACC
AAGTAACAGCACTTTTACAAGCAGCTAAAATCTCCTATGAAGACTTACTAATCAAGATAGAAATCAGAAAACAGTCCGAT
AAAACACGAAAGGAGCGCCTAGAAACTCTCAATCCTTTTTCTTTTAAAAATATTTCAAAAGTGCCAGAAAATATTTTGAT
TATTGATGATATTTACACAACTGGCGCTACTTTAAAGGGAATATACCAGCTTTTCTATGAAAATGGCGCAAAAAATGTAA
AAAGTTTTACGATTGTGCGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380K6H1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis NCTC 12261

50

100

0.5
  comFC/cflB Streptococcus pneumoniae TIGR4

49.545

100

0.495
  comFC/cflB Streptococcus pneumoniae Rx1

49.545

100

0.495
  comFC/cflB Streptococcus pneumoniae D39

49.545

100

0.495
  comFC/cflB Streptococcus pneumoniae R6

49.545

100

0.495
  comFC/cflB Streptococcus mitis SK321

49.091

100

0.491
  comFC Bacillus subtilis subsp. subtilis str. 168

34.934

100

0.364