Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   PY824_RS02585 Genome accession   NZ_CP119172
Coordinates   462430..463731 (+) Length   433 a.a.
NCBI ID   WP_115265995.1    Uniprot ID   -
Organism   Streptococcus macedonicus strain SGM CIP105683     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 457430..468731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY824_RS02560 (PY824_02560) - 458009..458653 (+) 645 WP_009853571.1 response regulator transcription factor -
  PY824_RS02565 (PY824_02565) - 458772..460172 (+) 1401 WP_115265993.1 Cof-type HAD-IIB family hydrolase -
  PY824_RS02570 (PY824_02570) - 460172..460528 (+) 357 WP_014294074.1 S1 RNA-binding domain-containing protein -
  PY824_RS02575 (PY824_02575) cysK 460648..461577 (-) 930 WP_014294075.1 cysteine synthase A -
  PY824_RS02580 (PY824_02580) - 461681..462373 (-) 693 WP_115265994.1 YigZ family protein -
  PY824_RS02585 (PY824_02585) comFA/cflA 462430..463731 (+) 1302 WP_115265995.1 DEAD/DEAH box helicase Machinery gene
  PY824_RS02590 (PY824_02590) comFC/cflB 463728..464390 (+) 663 WP_014294078.1 ComF family protein Machinery gene
  PY824_RS02595 (PY824_02595) raiA 464466..465014 (+) 549 WP_014294079.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49180.38 Da        Isoelectric Point: 9.9437

>NTDB_id=798039 PY824_RS02585 WP_115265995.1 462430..463731(+) (comFA/cflA) [Streptococcus macedonicus strain SGM CIP105683]
MDKLDNYYGRLFTQAQLSDALKKQTKQLPAMTKLNHHYVCNRCGSQVSLQNKLQTNVFYCRICLVFGRNTSNGHLYYFPQ
KCFSKKNSLIWKGKLTPYQDDISKGMLEGIDAKKDLLIHAVTGAGKTEMIYQSVSKIIDDGGCVCLASPRIDVCLELYKR
LSRDFSCPITLLHGDSESYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNAVLYHAVDKATKPNGTKIFLTATST
DELDKKVKTGTLTKLHLARRFHANPLVVPQKIWLSGILSNMQKKKIPQKLINLLKKQRQTRYPLLIFFPNIEQGEAFTQI
LQTYFPEEQIAFVSSKTENRLEIVEKFRKQELSILVTTTILERGVTFPCVDVFVVLANHRLYTKSALVQISGRVGRAAER
PTGELLFLHDGSTKEMRKAITEIKAMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=798039 PY824_RS02585 WP_115265995.1 462430..463731(+) (comFA/cflA) [Streptococcus macedonicus strain SGM CIP105683]
ATGGATAAACTGGATAATTATTATGGAAGACTATTTACACAAGCTCAACTTTCGGATGCCTTAAAAAAACAGACTAAACA
GTTACCAGCAATGACAAAATTAAATCATCATTATGTTTGCAATCGTTGTGGTAGTCAAGTATCTTTACAAAACAAACTTC
AAACAAACGTTTTTTATTGTCGAATTTGCCTTGTTTTTGGAAGAAATACGAGTAATGGACATCTCTATTATTTTCCACAA
AAATGTTTTTCTAAAAAAAATTCTCTTATTTGGAAAGGAAAATTGACTCCTTACCAAGATGACATTTCAAAAGGGATGTT
AGAAGGTATTGATGCTAAGAAAGATCTACTTATTCATGCTGTTACAGGTGCTGGAAAAACAGAAATGATTTACCAATCTG
TATCCAAAATAATTGATGACGGTGGTTGTGTTTGCCTAGCAAGTCCGCGAATTGATGTTTGTCTGGAACTTTATAAACGC
TTGTCACGTGATTTTTCGTGTCCGATTACATTGCTTCATGGAGATTCTGAGTCCTACAAACGTGCCCCTTTAATCATTGC
CACAACACATCAACTTTTAAAATTTTACCAAGCTTTTGATTTGTTAATTATTGATGAAGTTGATGCCTTTCCATTTGTGG
ATAATGCCGTGCTTTACCATGCTGTTGATAAAGCTACCAAACCTAATGGAACCAAGATTTTTTTAACAGCGACATCAACA
GATGAATTAGATAAAAAAGTAAAAACAGGAACTCTGACCAAATTGCACCTTGCTCGACGCTTTCATGCCAATCCATTAGT
TGTGCCACAAAAAATCTGGTTGTCTGGCATTTTATCCAATATGCAAAAGAAGAAAATTCCCCAGAAATTAATAAATCTTC
TGAAAAAACAACGTCAAACCCGCTATCCTTTGCTAATCTTCTTCCCAAACATCGAACAAGGAGAAGCCTTTACTCAAATT
TTACAAACTTACTTTCCAGAAGAACAAATCGCTTTTGTGTCTAGTAAAACAGAAAATCGCTTAGAAATTGTAGAAAAATT
TAGGAAACAAGAACTTTCTATTTTGGTTACAACAACCATTTTAGAACGTGGTGTCACTTTCCCATGCGTAGATGTTTTTG
TAGTGCTTGCCAATCATAGATTATATACCAAAAGCGCGCTAGTTCAGATTTCAGGGCGAGTTGGGAGAGCAGCAGAGCGT
CCAACAGGAGAACTGTTATTCTTGCATGACGGTAGCACTAAAGAAATGAGAAAAGCTATTACTGAAATTAAAGCGATGAA
TAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(97-244)

Helicase conserved C-terminal domain (Helicase_C)

(287-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae Rx1

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae D39

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae R6

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

59.251

98.614

0.584
  comFA/cflA Streptococcus mitis SK321

58.548

98.614

0.577
  comFA Lactococcus lactis subsp. cremoris KW2

50.476

96.998

0.49
  comFA Latilactobacillus sakei subsp. sakei 23K

38.283

99.538

0.381