Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   PYW40_RS07830 Genome accession   NZ_CP118979
Coordinates   1623716..1624582 (-) Length   288 a.a.
NCBI ID   WP_011275951.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain DSM 20263     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1605916..1654249 1623716..1624582 within 0


Gene organization within MGE regions


Location: 1605916..1654249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW40_RS07760 - 1607776..1609476 (-) 1701 WP_011275937.1 proline--tRNA ligase -
  PYW40_RS07765 rseP 1609495..1610781 (-) 1287 WP_011275938.1 RIP metalloprotease RseP -
  PYW40_RS07770 - 1610992..1611774 (-) 783 WP_037537321.1 phosphatidate cytidylyltransferase -
  PYW40_RS07775 - 1611778..1612548 (-) 771 WP_011275940.1 isoprenyl transferase -
  PYW40_RS07780 frr 1612774..1613328 (-) 555 WP_011275941.1 ribosome recycling factor -
  PYW40_RS07785 pyrH 1613346..1614068 (-) 723 WP_011275942.1 UMP kinase -
  PYW40_RS07790 tsf 1614205..1615083 (-) 879 WP_011275943.1 translation elongation factor Ts -
  PYW40_RS07795 rpsB 1615241..1616029 (-) 789 WP_011275944.1 30S ribosomal protein S2 -
  PYW40_RS07800 codY 1616296..1617069 (-) 774 WP_011275945.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  PYW40_RS07805 hslU 1617091..1618494 (-) 1404 WP_011275946.1 ATP-dependent protease ATPase subunit HslU -
  PYW40_RS07810 hslV 1618553..1619098 (-) 546 WP_011275947.1 ATP-dependent protease subunit HslV -
  PYW40_RS07815 xerC 1619099..1619962 (-) 864 WP_222127965.1 tyrosine recombinase XerC -
  PYW40_RS07820 trmFO 1620137..1621444 (-) 1308 WP_011275949.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  PYW40_RS07825 topA 1621468..1623537 (-) 2070 WP_011275950.1 type I DNA topoisomerase -
  PYW40_RS07830 dprA 1623716..1624582 (-) 867 WP_011275951.1 DNA-processing protein DprA Machinery gene
  PYW40_RS07835 - 1624801..1626030 (-) 1230 WP_011275952.1 aminoacyltransferase -
  PYW40_RS07840 sucD 1626330..1627235 (-) 906 WP_011275953.1 succinate--CoA ligase subunit alpha -
  PYW40_RS07845 sucC 1627257..1628423 (-) 1167 WP_011275954.1 ADP-forming succinate--CoA ligase subunit beta -
  PYW40_RS07850 - 1628535..1629302 (-) 768 WP_033080068.1 ribonuclease HII -
  PYW40_RS07855 ylqF 1629286..1630170 (-) 885 WP_011275956.1 ribosome biogenesis GTPase YlqF -
  PYW40_RS07860 - 1630413..1633007 (+) 2595 WP_011275957.1 YfhO family protein -
  PYW40_RS07865 - 1633009..1635618 (+) 2610 WP_037557998.1 YfhO family protein -
  PYW40_RS07870 rplS 1635776..1636126 (-) 351 WP_037537864.1 50S ribosomal protein L19 -
  PYW40_RS07875 trmD 1636231..1636968 (-) 738 WP_037557997.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  PYW40_RS07880 rimM 1636968..1637471 (-) 504 WP_037557996.1 ribosome maturation factor RimM -
  PYW40_RS07885 rpsP 1637590..1637865 (-) 276 WP_011275962.1 30S ribosomal protein S16 -
  PYW40_RS07890 ffh 1638111..1639481 (-) 1371 WP_037557994.1 signal recognition particle protein -
  PYW40_RS07895 - 1639507..1639839 (-) 333 WP_037537868.1 putative DNA-binding protein -
  PYW40_RS07900 ftsY 1639826..1641049 (-) 1224 WP_053017389.1 signal recognition particle-docking protein FtsY -
  PYW40_RS07905 smc 1641046..1644615 (-) 3570 WP_053017387.1 chromosome segregation protein SMC -
  PYW40_RS07910 rnc 1644700..1645452 (-) 753 WP_210423027.1 ribonuclease III -
  PYW40_RS07915 - 1645523..1645756 (-) 234 WP_001830184.1 acyl carrier protein -
  PYW40_RS07920 fabG 1645869..1646606 (-) 738 WP_011275968.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  PYW40_RS07925 fabD 1646596..1647525 (-) 930 WP_011275969.1 ACP S-malonyltransferase -
  PYW40_RS07930 plsX 1647518..1648504 (-) 987 WP_011275970.1 phosphate acyltransferase PlsX -
  PYW40_RS07935 fapR 1648506..1649066 (-) 561 WP_011275971.1 transcription factor FapR -
  PYW40_RS07940 recG 1649202..1651253 (-) 2052 WP_016930693.1 ATP-dependent DNA helicase RecG -
  PYW40_RS07945 - 1651408..1652208 (-) 801 WP_011275973.1 thermonuclease family protein -
  PYW40_RS07950 fakA 1652394..1654052 (-) 1659 WP_011275974.1 fatty acid kinase catalytic subunit FakA -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 33058.12 Da        Isoelectric Point: 9.4081

>NTDB_id=797122 PYW40_RS07830 WP_011275951.1 1623716..1624582(-) (dprA) [Staphylococcus haemolyticus strain DSM 20263]
MTNNNILLLKLIWLGYTTQHIHHLLKLNPEFFKFSYTDQIDSIKNWDKLFHKGDFIDRYNHLNDKEILSFLNQHKISFVT
PFNANYPRLLKEIYDYPFVLFYQGDPQLLTSPNTLGVVGSRNATEYSAKAMQYLFPKFKQIPLTIISGLAKGADSIAHHF
AIEYQLPTIAVLGFGHMMHYPRETQKLRNIIEVKGLVISEYPPFTSVRRYHFPQRNRLISGLSQGVLITEASVRSGSQIT
IDCALDQNRNIYVLPGSIFNPLTKGNLKRAQEGAMIVTSADDILCDYK

Nucleotide


Download         Length: 867 bp        

>NTDB_id=797122 PYW40_RS07830 WP_011275951.1 1623716..1624582(-) (dprA) [Staphylococcus haemolyticus strain DSM 20263]
ATGACTAACAACAACATATTACTTTTGAAATTAATTTGGTTAGGTTATACGACCCAACATATTCATCATTTATTAAAATT
AAATCCTGAATTTTTTAAATTCTCTTATACTGATCAAATAGATTCAATAAAAAATTGGGACAAGTTATTTCATAAAGGTG
ATTTTATTGATCGATATAATCATTTAAATGATAAAGAAATTTTGTCATTTTTGAATCAACACAAGATAAGTTTTGTAACA
CCGTTTAACGCTAATTATCCTCGACTATTAAAAGAAATTTATGATTATCCGTTTGTCCTATTTTACCAAGGTGACCCCCA
ATTATTAACATCCCCCAATACATTAGGTGTGGTGGGCTCAAGAAATGCAACAGAGTACTCAGCTAAAGCCATGCAATACT
TATTTCCTAAATTTAAACAAATTCCACTAACCATTATTTCCGGTTTGGCAAAAGGTGCTGATAGCATTGCACATCATTTT
GCTATAGAGTATCAATTACCTACTATAGCTGTTTTAGGTTTTGGTCATATGATGCATTACCCTAGAGAAACGCAAAAATT
ACGCAACATAATTGAAGTAAAAGGTTTAGTTATTAGTGAATATCCGCCATTCACTAGTGTTAGGCGATATCACTTTCCGC
AACGCAATCGTTTGATAAGCGGTCTTTCACAAGGGGTTTTAATAACTGAAGCAAGTGTTAGAAGCGGTAGTCAAATTACA
ATTGATTGCGCATTAGACCAAAATAGAAATATATATGTATTACCAGGTTCAATATTTAATCCACTAACTAAAGGTAATTT
GAAACGAGCTCAAGAAGGTGCGATGATTGTAACCTCAGCTGATGATATTCTATGTGATTATAAATAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

49.825

98.958

0.493
  dprA Staphylococcus aureus N315

49.825

98.958

0.493
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae D39

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae R6

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

36.395

100

0.372
  dprA Streptococcus mutans UA159

37.544

98.958

0.372
  dprA/cilB/dalA Streptococcus mitis SK321

35.374

100

0.361
  dprA Legionella pneumophila strain ERS1305867

42.105

85.764

0.361