Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PW252_RS11195 Genome accession   NZ_CP118735
Coordinates   2302489..2303664 (+) Length   391 a.a.
NCBI ID   WP_248049105.1    Uniprot ID   A0AA97AE96
Organism   Streptococcus iners strain 29887     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2297489..2308664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS11165 (PW252_11160) - 2298116..2300695 (+) 2580 WP_248049109.1 YfhO family protein -
  PW252_RS11185 (PW252_11180) - 2301119..2301793 (-) 675 WP_316716792.1 YoaK family protein -
  PW252_RS11190 (PW252_11185) rlmH 2301818..2302297 (-) 480 WP_105118495.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PW252_RS11195 (PW252_11190) htrA 2302489..2303664 (+) 1176 WP_248049105.1 S1C family serine protease Regulator
  PW252_RS11200 (PW252_11195) spo0J 2303730..2304488 (+) 759 WP_105124974.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 391 a.a.        Molecular weight: 40783.61 Da        Isoelectric Point: 4.3735

>NTDB_id=794760 PW252_RS11195 WP_248049105.1 2302489..2303664(+) (htrA) [Streptococcus iners strain 29887]
MKKYLKFTILFVVGFVGGLAGALTASIFQPQVQQASSAITSVSNVQYDNETSTTKAVEKVQNAVVSVINYQTAASNSLSA
IFGNIASSDELAVAGEGSGVIYKKDGNNAYIVTNTHVINNAEKIDILLASGEKVAGELVGADTYSDIAVIKITADKVTAV
AEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLINIQGQVI
GITSSKISSSSLTSSGVTVEGMGFAIPSNDAVTIINQLETDGKVSRPALGVHMVNLTDLSTIQLEKAGLSNTELTSGVIV
VSTQAGLPADGKFETYDVITEIDGDVIENKSDLQSALYKHQVGDTISITYYRNNKKETVDIKLTHSTEQLQ

Nucleotide


Download         Length: 1176 bp        

>NTDB_id=794760 PW252_RS11195 WP_248049105.1 2302489..2303664(+) (htrA) [Streptococcus iners strain 29887]
ATGAAAAAATATTTGAAATTCACCATTCTATTTGTAGTGGGCTTCGTGGGCGGATTAGCCGGTGCATTGACAGCATCCAT
CTTTCAACCACAAGTTCAGCAAGCTAGCTCTGCCATTACCAGTGTTAGCAATGTCCAATATGATAATGAAACATCGACAA
CCAAAGCTGTTGAAAAAGTACAAAATGCTGTTGTTTCCGTCATTAACTATCAAACTGCAGCAAGTAATAGCCTGAGTGCG
ATTTTTGGAAATATTGCTAGTTCCGACGAATTAGCAGTAGCTGGTGAGGGATCTGGGGTTATATATAAGAAAGATGGTAA
TAATGCCTATATCGTAACCAATACCCACGTAATCAATAATGCTGAAAAAATTGATATCCTTCTTGCTTCTGGAGAGAAAG
TGGCAGGGGAATTAGTGGGTGCTGACACCTACTCTGACATAGCTGTTATCAAAATAACTGCAGACAAGGTGACAGCAGTA
GCTGAATTTGCGGACTCAGACACCATTAAGGTTGGTGAAACAGCTATTGCAATCGGTAGCCCACTGGGTAGTGTCTATGC
AAATACTGTCACACAAGGAATTATTTCTAGCCTCAGTCGTACTGTCACCTCTCAGTCTGAAGATGGGCAAACCATTTCAA
CCAATGCTATTCAAACAGATACAGCTATTAACCCAGGTAACTCTGGTGGACCACTCATCAATATTCAAGGTCAAGTGATT
GGAATTACTTCTAGCAAAATTTCCTCCAGTTCTTTGACTAGTTCTGGTGTTACAGTTGAAGGTATGGGATTTGCAATTCC
TTCCAACGATGCGGTGACCATTATCAATCAACTAGAAACAGATGGTAAGGTCAGTCGACCTGCTCTGGGTGTTCACATGG
TTAACTTGACAGATTTGTCAACTATTCAACTTGAAAAAGCAGGACTTTCCAATACTGAATTAACATCTGGTGTTATCGTT
GTTTCTACACAAGCAGGCCTACCAGCAGATGGAAAATTTGAAACCTATGATGTTATTACTGAAATTGACGGAGATGTCAT
CGAAAATAAGAGTGATTTACAAAGTGCACTTTATAAGCATCAGGTCGGAGATACCATTAGCATCACCTATTATAGAAACA
ATAAGAAAGAAACTGTTGACATCAAGTTGACACACTCTACCGAACAACTTCAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(287-383)

Trypsin-like peptidase domain (Trypsin_2)

(97-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

59.698

100

0.606
  htrA Streptococcus mutans UA159

58.779

100

0.591
  htrA Streptococcus pneumoniae D39

57.398

100

0.575
  htrA Streptococcus pneumoniae TIGR4

57.398

100

0.575
  htrA Streptococcus pneumoniae R6

57.398

100

0.575
  htrA Streptococcus pneumoniae Rx1

57.398

100

0.575
  htrA Streptococcus mitis NCTC 12261

56.888

100

0.57