Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   PW252_RS00300 Genome accession   NZ_CP118735
Coordinates   50657..51580 (+) Length   307 a.a.
NCBI ID   WP_248051115.1    Uniprot ID   A0AA96VMB9
Organism   Streptococcus iners strain 29887     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 45657..56580
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS00285 (PW252_00285) - 47414..48682 (+) 1269 WP_248051119.1 MerR family transcriptional regulator -
  PW252_RS00290 (PW252_00290) ruvB 48876..49874 (+) 999 WP_105152787.1 Holliday junction branch migration DNA helicase RuvB -
  PW252_RS00295 (PW252_00295) - 49941..50555 (+) 615 WP_248051117.1 HAD-IA family hydrolase -
  PW252_RS00300 (PW252_00300) comR 50657..51580 (+) 924 WP_248051115.1 helix-turn-helix domain-containing protein Regulator
  PW252_RS00305 (PW252_00305) comR 51663..52571 (+) 909 WP_125183993.1 helix-turn-helix domain-containing protein Regulator
  PW252_RS00310 (PW252_00310) - 52806..54026 (+) 1221 WP_248051113.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  PW252_RS00315 (PW252_00315) - 54216..55730 (+) 1515 WP_248051112.1 quinol oxidase -

Sequence

Protein


Download         Length: 307 a.a.        Molecular weight: 35949.10 Da        Isoelectric Point: 4.3658

>NTDB_id=794708 PW252_RS00300 WP_248051115.1 50657..51580(+) (comR) [Streptococcus iners strain 29887]
MNDKEFGQRVRQLRETANLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDDYYDDLPEEEKIAIDAIQSTIDVFETKTAEFGQDILDDYFEQIHRKKQFSAND
LLIIQLYLINLRMEVKQSSDFQHFLDLVEKLPSQVELVEPGDLFILRDVMITSVGLLGQKEEFSYIPTLFEALDKIMQKT
QDFQKKPILNLLKWKYELLINKDKDAGTALYEEALLFARIIGNAHLIAKLEEDWQIDVKPAEYSGCV

Nucleotide


Download         Length: 924 bp        

>NTDB_id=794708 PW252_RS00300 WP_248051115.1 50657..51580(+) (comR) [Streptococcus iners strain 29887]
ATGAACGATAAGGAATTTGGTCAACGTGTGCGTCAACTGCGAGAAACTGCTAATCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATAGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTACGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTACTTCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGGGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCCGAGGAGGAGAAAATAGCAATCGATGCTATTCAATCAACCATTGACGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGATGACTATTTTGAACAGATACATAGAAAAAAACAATTTTCAGCCAATGAT
TTGTTGATAATCCAGCTCTATTTAATCAATTTGAGAATGGAAGTTAAACAGAGCAGTGATTTTCAGCACTTTTTAGACTT
GGTGGAAAAGTTACCAAGCCAAGTAGAATTAGTTGAACCTGGGGATTTGTTTATTTTAAGGGATGTGATGATAACTTCTG
TTGGACTTTTGGGACAAAAGGAAGAATTTAGCTATATTCCTACACTCTTTGAAGCACTTGATAAGATAATGCAGAAGACC
CAAGATTTTCAAAAGAAACCTATTCTTAATCTGCTTAAGTGGAAATATGAGTTGTTAATAAATAAAGATAAAGATGCAGG
AACTGCCTTATATGAAGAAGCACTTCTTTTTGCAAGAATAATTGGTAATGCCCACCTAATTGCTAAATTAGAAGAGGATT
GGCAAATAGATGTGAAACCAGCAGAATATTCAGGTTGTGTGTAA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

66.33

96.743

0.642
  comR Streptococcus suis 05ZYH33

66.33

96.743

0.642
  comR Streptococcus suis D9

59.801

98.046

0.586
  comR Streptococcus mutans UA159

42.424

96.743

0.41
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

41.356

96.091

0.397
  comR Streptococcus pyogenes MGAS8232

39.933

97.068

0.388