Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   PW252_RS00305 Genome accession   NZ_CP118735
Coordinates   51663..52571 (+) Length   302 a.a.
NCBI ID   WP_125183993.1    Uniprot ID   A0AA97A2S9
Organism   Streptococcus iners strain 29887     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 46663..57571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS00285 (PW252_00285) - 47414..48682 (+) 1269 WP_248051119.1 MerR family transcriptional regulator -
  PW252_RS00290 (PW252_00290) ruvB 48876..49874 (+) 999 WP_105152787.1 Holliday junction branch migration DNA helicase RuvB -
  PW252_RS00295 (PW252_00295) - 49941..50555 (+) 615 WP_248051117.1 HAD-IA family hydrolase -
  PW252_RS00300 (PW252_00300) comR 50657..51580 (+) 924 WP_248051115.1 helix-turn-helix domain-containing protein Regulator
  PW252_RS00305 (PW252_00305) comR 51663..52571 (+) 909 WP_125183993.1 helix-turn-helix domain-containing protein Regulator
  PW252_RS00310 (PW252_00310) - 52806..54026 (+) 1221 WP_248051113.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  PW252_RS00315 (PW252_00315) - 54216..55730 (+) 1515 WP_248051112.1 quinol oxidase -

Sequence

Protein


Download         Length: 302 a.a.        Molecular weight: 35661.65 Da        Isoelectric Point: 4.5061

>NTDB_id=794709 PW252_RS00305 WP_125183993.1 51663..52571(+) (comR) [Streptococcus iners strain 29887]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRAKLSIND
LMILRLFVEHCELETLASGTANYTLFIDLVEKLPQITYDVHSESLFIVRDLLLAIVRILFSKELYGYVPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKEKHNREGAERYFNEAVTLASLLNQIHLKEKLQMEWEQDTQS

Nucleotide


Download         Length: 909 bp        

>NTDB_id=794709 PW252_RS00305 WP_125183993.1 51663..52571(+) (comR) [Streptococcus iners strain 29887]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTTCGCCAACTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTACGAGCTTATGCCTGATTATGTATCTCTACCTGAACGGTATTCCAAACTGAAA
TTTGATGTCCTCCGAACACCGACTTATGGAAACGAGGAATTAGTTGAAAAACGCGATGCTATCATGACGGAAATCTATGA
TGACTACTATGATGACTTGCCTGAAGAGGAGAAAATCGTTGTAGATACCCTATGCTCTCTATTTGATGTATTGGATACAG
ATAGTCAGGAATACGGCAAAGAAATTCTTGATGATTATTTACATCAAAGTTACCATCGTGCCAAATTGTCTATAAATGAT
TTAATGATTTTGCGGTTATTTGTCGAACACTGTGAGTTAGAAACCTTAGCTTCTGGAACCGCAAATTATACACTATTTAT
AGATTTGGTAGAGAAATTACCTCAAATAACCTACGATGTGCATTCGGAATCCTTATTTATTGTCAGAGATTTATTGCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGCTGTATGGGTATGTTCCAGTCTATATAGAAAAAATTGAAAATATTATGGAA
TTATCGCAAGATTTTCAGAAAAAGCCAATTTTAAATCTGGTGAAATGGAAATATGAATTAAAGGAGAAACATAATCGCGA
AGGAGCCGAGAGATATTTTAATGAGGCTGTAACACTTGCTAGTCTATTGAATCAAATTCATTTGAAAGAAAAACTCCAAA
TGGAATGGGAACAAGATACCCAGAGCTAA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis D9

89.404

100

0.894
  comR Streptococcus suis P1/7

58.804

99.669

0.586
  comR Streptococcus suis 05ZYH33

58.804

99.669

0.586
  comR Streptococcus mutans UA159

37.333

99.338

0.371
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.801

96.358

0.364