Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PW220_RS10310 Genome accession   NZ_CP118734
Coordinates   2053512..2054687 (+) Length   391 a.a.
NCBI ID   WP_248055862.1    Uniprot ID   A0AA96VGR6
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2048512..2059687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS10280 (PW220_10285) - 2049132..2051711 (+) 2580 WP_248055861.1 YfhO family protein -
  PW220_RS10300 (PW220_10305) - 2052142..2052816 (-) 675 WP_105118494.1 YoaK family protein -
  PW220_RS10305 (PW220_10310) rlmH 2052841..2053320 (-) 480 WP_105118495.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PW220_RS10310 (PW220_10315) htrA 2053512..2054687 (+) 1176 WP_248055862.1 S1C family serine protease Regulator
  PW220_RS10315 (PW220_10320) spo0J 2054753..2055511 (+) 759 WP_105118497.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 391 a.a.        Molecular weight: 40707.52 Da        Isoelectric Point: 4.3735

>NTDB_id=794706 PW220_RS10310 WP_248055862.1 2053512..2054687(+) (htrA) [Streptococcus iners subsp. hyiners strain 29892]
MKKYLKFAILFVVGFVGGLAGALTAPLFQPQVQQASSAITSVSNVQYDNETSTTKAVEKVQNAVVSVINYQTAASNSLSA
IFGNIASSDELAVAGEGSGVIYKKDGNNAYIVTNTHVINNAEKIDILLASGEKVAGELVGADTYSDIAVIKITADKVTAV
AEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLINIQGQVI
GITSSKISSSSLTSSGVTVEGMGFAIPSNDAVAIINQLETDGKVSRPALGVHMVNLTDLSTSQLEKAGLSNTELTSGVIV
VSTQAGLPADGKFETYDVITEIDGDVIENKSDLQSALYKHQIGDSISITYYRNNKKETVDIKLTHSTEQLQ

Nucleotide


Download         Length: 1176 bp        

>NTDB_id=794706 PW220_RS10310 WP_248055862.1 2053512..2054687(+) (htrA) [Streptococcus iners subsp. hyiners strain 29892]
ATGAAAAAATATTTGAAATTCGCTATTCTATTTGTAGTTGGTTTTGTGGGCGGATTAGCTGGTGCATTGACAGCCCCCCT
ATTTCAACCTCAAGTCCAGCAAGCTAGCTCAGCTATTACTAGCGTCAGCAATGTCCAATATGATAATGAAACATCGACAA
CCAAAGCTGTCGAAAAAGTACAGAACGCTGTGGTTTCCGTGATTAACTATCAAACTGCAGCAAGTAATAGCCTGAGCGCT
ATTTTTGGAAATATTGCCAGTTCCGACGAATTAGCAGTAGCTGGTGAGGGATCTGGGGTTATATATAAGAAAGATGGTAA
TAATGCCTATATCGTAACCAATACCCACGTAATCAATAATGCTGAAAAAATTGATATCCTTCTAGCTTCTGGAGAGAAAG
TAGCTGGGGAATTAGTGGGTGCTGACACCTACTCTGACATAGCTGTTATCAAAATCACTGCAGACAAGGTGACAGCAGTA
GCTGAATTTGCGGACTCAGACACCATTAAGGTTGGTGAAACAGCTATTGCAATCGGTAGTCCTCTAGGGAGTGTTTACGC
AAATACCGTCACACAGGGGATTATCTCCAGCCTCAGTCGTACTGTCACCTCTCAGTCTGAAGATGGGCAAACCATTTCAA
CCAATGCTATTCAAACAGATACAGCTATTAACCCAGGTAACTCTGGTGGACCACTCATCAATATTCAAGGTCAAGTGATC
GGAATTACTTCTAGCAAAATTTCCTCCAGTTCTTTGACTAGTTCTGGTGTTACAGTTGAAGGTATGGGATTTGCAATTCC
TTCCAACGATGCGGTGGCCATTATCAATCAACTGGAAACAGATGGTAAGGTCAGTCGACCTGCTCTGGGTGTTCACATGG
TTAACTTGACAGATTTGTCAACTAGTCAACTTGAAAAAGCAGGACTTTCCAACACTGAATTAACATCTGGTGTTATCGTT
GTTTCTACACAAGCAGGCCTACCAGCAGATGGAAAATTTGAAACCTATGATGTTATTACTGAAATTGACGGGGATGTCAT
CGAAAATAAAAGTGATCTACAGAGTGCGCTTTATAAGCACCAAATTGGAGATAGCATAAGCATCACCTATTATAGAAACA
ATAAGAAAGAAACTGTTGACATCAAGTTGACACACTCTACCGAACAACTTCAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(287-383)

Trypsin-like peptidase domain (Trypsin_2)

(97-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

59.95

100

0.609
  htrA Streptococcus mutans UA159

59.033

100

0.593
  htrA Streptococcus pneumoniae D39

57.908

100

0.581
  htrA Streptococcus pneumoniae TIGR4

57.908

100

0.581
  htrA Streptococcus pneumoniae R6

57.908

100

0.581
  htrA Streptococcus pneumoniae Rx1

57.908

100

0.581
  htrA Streptococcus mitis NCTC 12261

57.398

100

0.575