Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   KH172YL63_RS06190 Genome accession   NZ_AP022842
Coordinates   1244180..1246003 (+) Length   607 a.a.
NCBI ID   WP_173105285.1    Uniprot ID   A0A6F8TNX4
Organism   Bacillus sp. KH172YL63     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1239180..1251003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KH172YL63_RS06170 (KH172YL63_11760) spxA 1239520..1239915 (+) 396 WP_138777213.1 transcriptional regulator SpxA -
  KH172YL63_RS06175 (KH172YL63_11770) mecA 1240268..1240939 (+) 672 WP_173105282.1 adaptor protein MecA Regulator
  KH172YL63_RS06180 (KH172YL63_11780) cls 1241037..1242542 (+) 1506 WP_173105283.1 cardiolipin synthase -
  KH172YL63_RS06185 (KH172YL63_11790) - 1242784..1243986 (+) 1203 WP_173105284.1 competence protein CoiA family protein -
  KH172YL63_RS06190 (KH172YL63_11800) pepF 1244180..1246003 (+) 1824 WP_173105285.1 oligoendopeptidase F Regulator
  KH172YL63_RS06195 (KH172YL63_11810) - 1246052..1246240 (-) 189 WP_232066135.1 hypothetical protein -
  KH172YL63_RS06200 (KH172YL63_11820) - 1246524..1247387 (-) 864 WP_232066136.1 ClpXP adapter SpxH family protein -
  KH172YL63_RS06205 (KH172YL63_11830) - 1247380..1247775 (-) 396 WP_173105287.1 globin -
  KH172YL63_RS06210 (KH172YL63_11840) - 1248066..1248707 (-) 642 WP_173105288.1 lytic transglycosylase domain-containing protein -
  KH172YL63_RS06215 (KH172YL63_11850) - 1248759..1249340 (-) 582 WP_173105289.1 CYTH domain-containing protein -
  KH172YL63_RS06220 (KH172YL63_11860) - 1249470..1249844 (+) 375 WP_173105290.1 hypothetical protein -
  KH172YL63_RS06225 (KH172YL63_11870) - 1249871..1250518 (+) 648 WP_173105291.1 GTP pyrophosphokinase family protein -

Sequence

Protein


Download         Length: 607 a.a.        Molecular weight: 70305.66 Da        Isoelectric Point: 4.6419

>NTDB_id=79335 KH172YL63_RS06190 WP_173105285.1 1244180..1246003(+) (pepF) [Bacillus sp. KH172YL63]
MSKDTAVKSLPGRKDVEENLTWRLEDIFESDEAWEKEYKEIKQLTGRAEEFKGTLADSADQLYKAFAFQDEIMERMGKVY
TYSHMRYDQDTTNSYYQGLDDRAKSLYTQLGSKFAYLVPEILSIDEEKLKGFLDEKKELQQYKHALEEINLERPHILSAE
EEALLAQASEVFSASSNTFGMLNNADLEFPTITDENGEEVDITHGRFIRFLESSDRRVRQEAFKKVYETYGQFENTFAST
LSGAVKKDNFIANVRHYDSARHAALSNNNIPEEVYDNLVGTVNKNLHLLQRYVKLRKKVLGLDEVHMYDLYTPLVKEVKM
DISYDEAQQMILDGLKPLGEEYANVLKEGFESRWVDVVENKGKRSGAYSSGAYGTNPYILMNWQDNVNNLFTLAHEFGHS
VHSYYTRKTQPYTYGHYSIFVAEVASTCNEALLNDYLLNTIEDEKKRLYLLNHYLEGFRGTVFRQTMFAEFEHLIHKKAQ
EGEALTSEFLTKEYYELNKKYFGDDIAIDEEIGLEWARIPHFYYNYYVYQYATGFSAATALSQQILEEGEPAVERYIDFL
KAGSSDYPIEVLKKAGVDVTTTKPVEDACKVFEEKLNEMEELLEKLQ

Nucleotide


Download         Length: 1824 bp        

>NTDB_id=79335 KH172YL63_RS06190 WP_173105285.1 1244180..1246003(+) (pepF) [Bacillus sp. KH172YL63]
ATGTCAAAAGATACAGCTGTAAAAAGCCTGCCCGGCAGGAAAGACGTCGAAGAGAATTTAACGTGGAGATTGGAAGATAT
TTTCGAAAGTGATGAAGCGTGGGAGAAGGAATATAAAGAAATCAAACAATTAACGGGGCGTGCAGAAGAGTTTAAAGGTA
CACTCGCAGACAGCGCAGATCAATTATACAAAGCATTTGCCTTCCAGGATGAAATAATGGAACGTATGGGGAAGGTATAT
ACATATTCTCATATGCGCTATGATCAGGATACGACCAATTCATATTACCAGGGACTAGATGATCGTGCAAAGAGCCTGTA
TACGCAACTTGGAAGCAAGTTTGCCTACCTTGTGCCTGAAATCCTGTCAATTGATGAGGAGAAGCTCAAGGGATTCCTTG
ATGAGAAGAAAGAACTGCAGCAGTACAAACATGCACTCGAAGAGATCAACCTCGAACGCCCTCACATCCTTTCAGCTGAA
GAAGAGGCGCTGCTTGCCCAGGCATCCGAGGTGTTCAGTGCTTCAAGCAATACATTTGGTATGTTGAACAATGCGGATCT
TGAGTTTCCAACCATTACAGATGAAAATGGGGAAGAAGTGGACATCACACACGGACGTTTCATCCGCTTCCTTGAGAGCA
GCGACCGCCGTGTCCGCCAAGAAGCATTCAAGAAGGTATATGAAACGTATGGACAGTTTGAGAATACATTTGCATCCACT
TTAAGCGGTGCAGTAAAGAAAGATAACTTCATCGCCAATGTAAGGCATTATGATTCAGCGCGGCATGCGGCGCTGTCGAA
TAACAACATCCCGGAAGAGGTGTATGATAACCTGGTCGGCACAGTCAATAAGAACCTTCATCTCCTGCAGCGGTATGTGA
AGCTCCGTAAAAAAGTGCTCGGCTTGGATGAAGTTCATATGTATGACCTGTATACACCACTTGTCAAAGAAGTGAAGATG
GACATCAGCTATGATGAAGCACAACAGATGATCCTTGACGGACTGAAACCGCTTGGCGAGGAATATGCCAATGTGCTGAA
AGAAGGCTTTGAAAGCCGCTGGGTGGATGTAGTCGAGAACAAAGGTAAACGAAGCGGCGCCTATTCATCCGGTGCTTATG
GCACCAATCCATACATCCTCATGAACTGGCAGGATAATGTGAATAATCTATTCACACTCGCCCATGAGTTCGGCCACAGT
GTACACAGCTACTATACGAGAAAAACCCAGCCATATACTTATGGCCATTATTCCATCTTCGTTGCAGAAGTGGCATCCAC
ATGCAATGAAGCATTATTGAATGATTACTTGTTGAACACGATCGAGGACGAAAAGAAGCGCCTTTACCTGTTGAATCATT
ATCTGGAAGGCTTCAGGGGCACGGTATTCCGCCAAACGATGTTTGCAGAGTTCGAACATCTCATCCATAAAAAGGCGCAG
GAAGGAGAGGCGCTTACTTCTGAATTCCTCACGAAAGAGTACTATGAATTGAACAAGAAATATTTCGGCGATGACATTGC
GATCGACGAAGAAATTGGGCTGGAGTGGGCACGGATCCCGCACTTCTATTACAATTATTATGTATACCAGTACGCAACAG
GATTCTCGGCTGCAACCGCGCTCAGTCAACAAATCCTTGAAGAAGGCGAACCTGCTGTAGAACGGTACATTGACTTCCTG
AAAGCAGGAAGCTCCGACTACCCGATTGAAGTATTGAAGAAGGCCGGCGTCGATGTGACTACCACTAAACCTGTGGAAGA
TGCATGCAAAGTATTTGAAGAAAAGTTAAATGAAATGGAAGAGCTGCTGGAGAAGCTTCAGTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(120-189)

Peptidase family M3 (Peptidase_M3)

(211-589)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6F8TNX4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

50.927

97.694

0.498

Multiple sequence alignment