Detailed information NTG0792723

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PWK66_RS04995
• Genome accession: NZ_CP118482
• Coordinates: 958266..959102 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 20160179
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 953266..964102

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PWK66_RS04965 (PWK66_04910)	-	953748..954188 (+)	441	WP_024623381.1	hypothetical protein	-
PWK66_RS04970 (PWK66_04915)	-	954238..955149 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
PWK66_RS04975 (PWK66_04920)	-	955266..955916 (-)	651	WP_002984629.1	hemolysin III family protein	-
PWK66_RS04980 (PWK66_04925)	-	955913..956353 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
PWK66_RS04985 (PWK66_04930)	ylqF	956572..957420 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
PWK66_RS04990 (PWK66_04935)	-	957410..958201 (+)	792	WP_002989771.1	ribonuclease HII	-
PWK66_RS04995 (PWK66_04940)	dprA	958266..959102 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
PWK66_RS05000 (PWK66_04945)	topA	959209..961338 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
PWK66_RS05005 (PWK66_04950)	-	961413..962270 (-)	858	Protein_939	LysR family transcriptional regulator	-
PWK66_RS05010 (PWK66_04955)	-	962310..962876 (+)	567	Protein_940	PTS sugar transporter subunit IIC	-
PWK66_RS05015 (PWK66_04960)	-	962891..963883 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=792723 PWK66_RS04995 WP_002989770.1 958266..959102(+) (dprA) [Streptococcus pyogenes strain 20160179]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=792723 PWK66_RS04995 WP_002989770.1 958266..959102(+) (dprA) [Streptococcus pyogenes strain 20160179]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367