Detailed information NTG0792669

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PWK65_RS04690
• Genome accession: NZ_CP118481
• Coordinates: 916877..917713 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 20185322
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 911877..922713

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PWK65_RS04660 (PWK65_04605)	-	912359..912799 (+)	441	WP_002989779.1	hypothetical protein	-
PWK65_RS04665 (PWK65_04610)	-	912849..913760 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
PWK65_RS04670 (PWK65_04615)	-	913877..914527 (-)	651	WP_002984629.1	hemolysin III family protein	-
PWK65_RS04675 (PWK65_04620)	-	914524..914964 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
PWK65_RS04680 (PWK65_04625)	ylqF	915183..916031 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
PWK65_RS04685 (PWK65_04630)	-	916021..916812 (+)	792	WP_002989771.1	ribonuclease HII	-
PWK65_RS04690 (PWK65_04635)	dprA	916877..917713 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
PWK65_RS04695 (PWK65_04640)	topA	917820..919949 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
PWK65_RS04700 (PWK65_04645)	-	920024..920881 (-)	858	Protein_878	LysR family transcriptional regulator	-
PWK65_RS04705 (PWK65_04650)	-	920921..921487 (+)	567	Protein_879	PTS sugar transporter subunit IIC	-
PWK65_RS04710 (PWK65_04655)	-	921502..922494 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=792669 PWK65_RS04690 WP_002989770.1 916877..917713(+) (dprA) [Streptococcus pyogenes strain 20185322]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=792669 PWK65_RS04690 WP_002989770.1 916877..917713(+) (dprA) [Streptococcus pyogenes strain 20185322]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367