Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EsVE80_RS10260 Genome accession   NZ_AP022822
Coordinates   2162635..2163897 (+) Length   420 a.a.
NCBI ID   WP_173103624.1    Uniprot ID   -
Organism   Enterococcus saigonensis strain VE80     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2157635..2168897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EsVE80_RS10230 (EsVE80_19980) - 2157800..2159305 (+) 1506 WP_173103618.1 helix-turn-helix domain-containing protein -
  EsVE80_RS10235 (EsVE80_19990) - 2159637..2159855 (-) 219 WP_173103619.1 hypothetical protein -
  EsVE80_RS10240 (EsVE80_20000) - 2159877..2160443 (-) 567 WP_173103620.1 hypothetical protein -
  EsVE80_RS10245 (EsVE80_20010) - 2160463..2160882 (-) 420 WP_173103621.1 MarR family winged helix-turn-helix transcriptional regulator -
  EsVE80_RS10250 (EsVE80_20020) - 2161176..2161688 (-) 513 WP_173103622.1 DUF1456 family protein -
  EsVE80_RS10255 (EsVE80_20030) rlmH 2161792..2162271 (-) 480 WP_173103623.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EsVE80_RS10260 (EsVE80_20040) htrA 2162635..2163897 (+) 1263 WP_173103624.1 S1C family serine protease Regulator
  EsVE80_RS10265 (EsVE80_20050) ytpR 2164045..2164653 (-) 609 WP_173103625.1 YtpR family tRNA-binding protein -
  EsVE80_RS10270 (EsVE80_20060) - 2164743..2165210 (-) 468 WP_173103626.1 universal stress protein -
  EsVE80_RS10275 (EsVE80_20070) - 2165225..2165545 (-) 321 WP_173103627.1 thioredoxin family protein -
  EsVE80_RS10280 (EsVE80_20080) pepA 2165637..2166716 (-) 1080 WP_173103628.1 glutamyl aminopeptidase -
  EsVE80_RS10285 (EsVE80_20090) - 2166932..2167279 (+) 348 WP_173103629.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 43502.41 Da        Isoelectric Point: 4.6601

>NTDB_id=79256 EsVE80_RS10260 WP_173103624.1 2162635..2163897(+) (htrA) [Enterococcus saigonensis strain VE80]
MQRKKSGGTFSRFLVGLLGGVLGAVLVGGGYLLATGADLQPNNNATEQTTTASGDTKVSNVKVNADTDITSAVDKVQDAV
VSVINLQKQQASSSNPFGDLFGQGQSEAESESDSESGGLQAVGEGSGVIYKKDGKTAYVVTNNHVVEGQDGLEVVLKNGE
KIKAELVGTDSYTDLAVLKISSDKVDKTATFGDSSELKVGEPAIAIGSPLGSQYANSVTSGIISSLNRQVADSQTGVNIS
AIQTDAAINPGNSGGPLVNIAGQVIGINSSKIASTNSSSSDISVEGMGFAIPSNDVVSIINQLEKNGKVIRPALGITMVD
LSAVTSQQQEQILKVPNTVKNGVVITSVQNATPAEQAGLKQYDVITKLDGKEVDSSSDLQSALYKKKVGDSIEITYYRGS
KEHTTKVSLTIDQSALKQNN

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=79256 EsVE80_RS10260 WP_173103624.1 2162635..2163897(+) (htrA) [Enterococcus saigonensis strain VE80]
ATGCAAAGAAAAAAATCAGGAGGCACATTTAGCCGTTTTTTAGTCGGATTATTAGGTGGTGTCTTAGGGGCTGTCTTAGT
CGGAGGCGGCTACTTATTAGCTACAGGAGCAGACTTGCAACCAAATAATAACGCAACTGAACAAACAACCACTGCAAGTG
GAGATACCAAAGTCTCAAATGTCAAAGTCAATGCAGATACAGATATTACCTCAGCGGTGGATAAAGTCCAAGATGCAGTT
GTTTCTGTCATTAACTTACAAAAACAACAAGCCTCATCAAGTAATCCTTTTGGCGATTTATTTGGTCAAGGACAATCTGA
AGCAGAATCTGAAAGTGATAGCGAATCAGGTGGCTTACAAGCTGTCGGTGAAGGTAGTGGTGTCATTTATAAAAAAGACG
GTAAAACCGCTTATGTTGTAACCAATAATCACGTTGTTGAAGGACAAGATGGTTTGGAAGTCGTTTTAAAGAATGGTGAA
AAAATCAAAGCTGAGTTAGTTGGAACAGACAGTTATACCGATTTGGCTGTTTTAAAAATCAGCAGTGATAAAGTTGATAA
AACAGCTACGTTCGGCGATTCTTCAGAATTAAAAGTTGGCGAACCTGCGATTGCTATCGGCTCCCCACTCGGTTCACAAT
ATGCAAACTCTGTAACCTCTGGGATTATTTCTTCATTAAATCGCCAAGTAGCTGATTCTCAAACCGGCGTCAATATCAGT
GCGATTCAAACAGATGCTGCGATTAATCCGGGTAACTCTGGTGGCCCATTAGTAAATATCGCTGGTCAAGTGATTGGAAT
TAACTCAAGTAAAATTGCTTCAACAAATTCTTCAAGCTCTGATATTAGTGTTGAAGGCATGGGCTTTGCCATTCCAAGTA
ACGATGTAGTCTCCATTATTAATCAGCTTGAGAAAAATGGTAAAGTTATTCGTCCAGCACTTGGTATTACTATGGTTGAC
TTATCTGCGGTAACGTCACAACAACAAGAACAAATTTTGAAAGTACCAAATACTGTAAAAAACGGCGTGGTTATCACTTC
TGTTCAAAATGCTACGCCAGCAGAGCAAGCTGGTTTAAAACAATATGATGTTATTACAAAACTTGATGGAAAAGAAGTTG
ATTCCAGTTCTGATTTGCAATCTGCTTTATACAAGAAAAAAGTTGGCGATTCCATTGAAATTACTTACTACCGTGGTAGT
AAAGAACACACAACTAAAGTTTCATTAACTATTGATCAGTCTGCTTTAAAGCAAAATAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(125-267)

PDZ domain (PDZ_2)

(312-409)

Peptidase family M50 (Peptidase_M50)

(282-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.041

97.857

0.519
  htrA Streptococcus mutans UA159

53.218

96.19

0.512
  htrA Streptococcus mitis NCTC 12261

52.957

88.571

0.469
  htrA Streptococcus pneumoniae TIGR4

56.268

81.667

0.46
  htrA Streptococcus pneumoniae Rx1

56.268

81.667

0.46
  htrA Streptococcus pneumoniae D39

56.268

81.667

0.46
  htrA Streptococcus pneumoniae R6

56.268

81.667

0.46

Multiple sequence alignment