Detailed information NTG0791757

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PVK50_RS05545
• Genome accession: NZ_CP118311
• Coordinates: 1080075..1080911 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 20164915
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1075075..1085911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PVK50_RS05525 (PVK50_05480)	-	1075294..1076286 (-)	993	WP_002989762.1	D-lactate dehydrogenase	-
PVK50_RS05530 (PVK50_05485)	-	1076301..1076867 (-)	567	Protein_1034	PTS sugar transporter subunit IIC	-
PVK50_RS05535 (PVK50_05490)	-	1076907..1077764 (+)	858	Protein_1035	LysR family transcriptional regulator	-
PVK50_RS05540 (PVK50_05495)	topA	1077839..1079968 (-)	2130	WP_002989768.1	type I DNA topoisomerase	-
PVK50_RS05545 (PVK50_05500)	dprA	1080075..1080911 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
PVK50_RS05550 (PVK50_05505)	-	1080976..1081767 (-)	792	WP_002989771.1	ribonuclease HII	-
PVK50_RS05555 (PVK50_05510)	ylqF	1081757..1082605 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
PVK50_RS05560 (PVK50_05515)	-	1082824..1083264 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
PVK50_RS05565 (PVK50_05520)	-	1083261..1083911 (+)	651	WP_002984629.1	hemolysin III family protein	-
PVK50_RS05570 (PVK50_05525)	-	1084028..1084939 (+)	912	WP_002989777.1	diacylglycerol kinase family protein	-
PVK50_RS05575 (PVK50_05530)	-	1084989..1085495 (-)	507	WP_397610624.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=791757 PVK50_RS05545 WP_002989770.1 1080075..1080911(-) (dprA) [Streptococcus pyogenes strain 20164915]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=791757 PVK50_RS05545 WP_002989770.1 1080075..1080911(-) (dprA) [Streptococcus pyogenes strain 20164915]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367