Detailed information NTG0791706

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PVK51_RS06460
• Genome accession: NZ_CP118310
• Coordinates: 1230345..1231181 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 20154051
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1225345..1236181

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PVK51_RS06440 (PVK51_06400)	-	1225564..1226556 (-)	993	WP_002989762.1	D-lactate dehydrogenase	-
PVK51_RS06445 (PVK51_06405)	-	1226571..1227137 (-)	567	Protein_1216	PTS sugar transporter subunit IIC	-
PVK51_RS06450 (PVK51_06410)	-	1227177..1228034 (+)	858	Protein_1217	LysR family transcriptional regulator	-
PVK51_RS06455 (PVK51_06415)	topA	1228109..1230238 (-)	2130	WP_002989768.1	type I DNA topoisomerase	-
PVK51_RS06460 (PVK51_06420)	dprA	1230345..1231181 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
PVK51_RS06465 (PVK51_06425)	-	1231246..1232037 (-)	792	WP_002989771.1	ribonuclease HII	-
PVK51_RS06470 (PVK51_06430)	ylqF	1232027..1232875 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
PVK51_RS06475 (PVK51_06435)	-	1233094..1233534 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
PVK51_RS06480 (PVK51_06440)	-	1233531..1234181 (+)	651	WP_002984629.1	hemolysin III family protein	-
PVK51_RS06485 (PVK51_06445)	-	1234298..1235209 (+)	912	WP_002989777.1	diacylglycerol kinase family protein	-
PVK51_RS06490 (PVK51_06450)	-	1235259..1235765 (-)	507	WP_397610624.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=791706 PVK51_RS06460 WP_002989770.1 1230345..1231181(-) (dprA) [Streptococcus pyogenes strain 20154051]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=791706 PVK51_RS06460 WP_002989770.1 1230345..1231181(-) (dprA) [Streptococcus pyogenes strain 20154051]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367