Detailed information NTG0791485

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: PVK49_RS06945
• Genome accession: NZ_CP118306
• Coordinates: 1393404..1394405 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain 20154608
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1388404..1399405

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PVK49_RS06930 (PVK49_06920)	thrS	1388575..1390518 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
PVK49_RS06935 (PVK49_06925)	-	1390940..1392274 (-)	1335	WP_047235925.1	glycosyltransferase family 4 protein	-
PVK49_RS06940 (PVK49_06930)	-	1392276..1393274 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
PVK49_RS06945 (PVK49_06935)	ccpA	1393404..1394405 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
PVK49_RS06950 (PVK49_06940)	-	1394579..1395664 (+)	1086	WP_047235926.1	aminopeptidase P family protein	-
PVK49_RS06955 (PVK49_06945)	-	1395713..1396378 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
PVK49_RS06960 (PVK49_06950)	-	1396389..1396766 (+)	378	WP_047235927.1	VOC family protein	-
PVK49_RS06965 (PVK49_06955)	-	1396911..1397837 (+)	927	WP_047235928.1	glycosyltransferase family 2 protein	-
PVK49_RS06970 (PVK49_06960)	-	1398046..1398729 (+)	684	WP_012560521.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=791485 PVK49_RS06945 WP_002985680.1 1393404..1394405(-) (ccpA) [Streptococcus pyogenes strain 20154608]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=791485 PVK49_RS06945 WP_002985680.1 1393404..1394405(-) (ccpA) [Streptococcus pyogenes strain 20154608]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCCGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559