Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   PVK49_RS06890 Genome accession   NZ_CP118306
Coordinates   1380776..1381486 (-) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 20154608     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1375776..1386486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVK49_RS06875 (PVK49_06865) rnc 1377472..1378164 (-) 693 WP_002990670.1 ribonuclease III -
  PVK49_RS06880 (PVK49_06870) vicX 1378618..1379427 (-) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  PVK49_RS06885 (PVK49_06875) vicK 1379431..1380783 (-) 1353 WP_002990673.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PVK49_RS06890 (PVK49_06880) vicR 1380776..1381486 (-) 711 WP_002985645.1 response regulator YycF Regulator
  PVK49_RS06895 (PVK49_06885) - 1381648..1382682 (-) 1035 WP_172448820.1 DUF3114 domain-containing protein -
  PVK49_RS06900 (PVK49_06890) - 1382738..1383985 (-) 1248 WP_014407393.1 AMP-binding protein -
  PVK49_RS06905 (PVK49_06895) - 1383942..1385090 (-) 1149 WP_032464243.1 acetyl-CoA C-acyltransferase -
  PVK49_RS06910 (PVK49_06900) - 1385485..1385634 (-) 150 WP_047235923.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=791484 PVK49_RS06890 WP_002985645.1 1380776..1381486(-) (vicR) [Streptococcus pyogenes strain 20154608]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=791484 PVK49_RS06890 WP_002985645.1 1380776..1381486(-) (vicR) [Streptococcus pyogenes strain 20154608]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACCATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCGCGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACTCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ACACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364