Detailed information NTG0782240

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: PO908_RS03535
• Genome accession: NZ_CP117042
• Coordinates: 630169..632319 (+)
• Length: 716 a.a.
• NCBI ID: WP_003025436.1
• Uniprot ID: A0AAP6BMV2
• Organism: Streptococcus anginosus strain CGMH_KH1
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 625169..637319

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PO908_RS03510 (PO908_03495)	frr	625699..626256 (+)	558	WP_003034284.1	ribosome recycling factor	-
PO908_RS03515 (PO908_03500)	cvfB	626603..627457 (+)	855	WP_003025448.1	RNA-binding virulence regulatory protein CvfB	-
PO908_RS03520 (PO908_03505)	holA	627538..628575 (+)	1038	WP_021001445.1	DNA polymerase III subunit delta	-
PO908_RS03525 (PO908_03510)	-	628646..629251 (+)	606	WP_021001446.1	superoxide dismutase	-
PO908_RS03530 (PO908_03515)	-	629314..629688 (-)	375	WP_037590248.1	hypothetical protein	-
PO908_RS03535 (PO908_03520)	comA/nlmT	630169..632319 (+)	2151	WP_003025436.1	peptide cleavage/export ABC transporter	Regulator
PO908_RS03540 (PO908_03525)	-	632330..633691 (+)	1362	WP_021001448.1	bacteriocin secretion accessory protein	-
PO908_RS03545 (PO908_03530)	-	633784..633933 (+)	150	WP_003025431.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
PO908_RS03550 (PO908_03535)	-	633978..635285 (-)	1308	WP_021001449.1	sensor histidine kinase	-
PO908_RS03555 (PO908_03540)	comE/blpR	635290..636036 (-)	747	WP_037590320.1	response regulator transcription factor	Regulator
PO908_RS03560 (PO908_03545)	-	636205..636918 (-)	714	WP_021001450.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80424.99 Da
• Isoelectric Point: 9.4752

>NTDB_id=782240 PO908_RS03535 WP_003025436.1 630169..632319(+) (comA/nlmT) [Streptococcus anginosus strain CGMH_KH1]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKAKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLTSFLPLI
FKQRSLIFYIVLASLLVTLINIVSSYYLQGILDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIILSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLFILIMVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEETRYQKIDSEFVNYLDKSFTLSKYSIMQTSLKQGAQFI
LNVVILWVGASLAMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQVITEKNFLA
GDITFHDVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILANLTLGTNQIFSQEEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHTKLMERKGFYHHLFSK

Nucleotide

• Length: 2151 bp

>NTDB_id=782240 PO908_RS03535 WP_003025436.1 630169..632319(+) (comA/nlmT) [Streptococcus anginosus strain CGMH_KH1]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGCTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACTAAGATATCAAAAGAGACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAGAATGGGCTTACTAGCTTTTTACCACTCATC
TTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTTGTGACCCTCATTAACATTGTTAGTTCTTATTA
TCTGCAAGGGATTTTGGATGAATACATTCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTATACTTAGTCAGCGATTAACCATCGATGTA
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAAATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTTTATTTTGATAA
TGGTAGGAGGGGTACTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACAGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTTATGCAAAGTAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACGATTAAATCTTTAACCAGCGAAGAAACTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCCATTATGCAGACATCTCTCAAACAAGGAGCACAATTTATT
TTGAATGTTGTTATTCTATGGGTTGGAGCATCTCTGGCTATGTCTCAAAAAATTTCGATTGGACAGCTGATTACTTTTAA
TGCACTCCTTTCGTATTTTACAAGTCCACTTGAAAGTATCATCAATCTGCAAACTAAGCTGCAGTCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATCTGGTAGAATCCGAATTCAAAACCAAACAAGTCATTACAGAGAAAAATTTCTTGGCT
GGTGACATTACTTTTCATGATGTTTCTTATAAATATGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTTAATGGAAATGATCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCCATCTTAGCAAATCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGATGAGGCAACGAGCGGATTGGATGTTTTAACTGAGAAAAAGGTCATTGACAATCTGATGGGCTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAAGTGATTGTTCTTGATAAAGGACAGA
TTATTGAAACTGGTTCCCACACTAAATTGATGGAAAGAAAAGGTTTTTATCATCATTTATTTAGCAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (167-437)

• ABC transporter (ABC_tran) (499-648)

• Peptidase C39 family (Peptidase_C39) (6-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.227	99.022	0.705
comA	Streptococcus mitis NCTC 12261	66.245	99.302	0.658
comA	Streptococcus mitis SK321	65.963	99.302	0.655
comA	Streptococcus gordonii str. Challis substr. CH1	65.541	99.302	0.651
comA	Streptococcus pneumoniae D39	65.401	99.302	0.649
comA	Streptococcus pneumoniae R6	65.401	99.302	0.649
comA	Streptococcus pneumoniae Rx1	65.401	99.302	0.649
comA	Streptococcus pneumoniae TIGR4	64.979	99.302	0.645