Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   PO908_RS03555 Genome accession   NZ_CP117042
Coordinates   635290..636036 (-) Length   248 a.a.
NCBI ID   WP_037590320.1    Uniprot ID   A0AAP6EN96
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 630290..641036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS03540 (PO908_03525) - 632330..633691 (+) 1362 WP_021001448.1 bacteriocin secretion accessory protein -
  PO908_RS03545 (PO908_03530) - 633784..633933 (+) 150 WP_003025431.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  PO908_RS03550 (PO908_03535) - 633978..635285 (-) 1308 WP_021001449.1 sensor histidine kinase -
  PO908_RS03555 (PO908_03540) comE/blpR 635290..636036 (-) 747 WP_037590320.1 response regulator transcription factor Regulator
  PO908_RS03560 (PO908_03545) - 636205..636918 (-) 714 WP_021001450.1 CPBP family intramembrane glutamic endopeptidase -
  PO908_RS03565 (PO908_03550) - 637181..638023 (-) 843 WP_232043636.1 IS3 family transposase -
  PO908_RS03570 (PO908_03555) - 638038..638319 (-) 282 WP_021001851.1 IS3 family transposase -
  PO908_RS03575 (PO908_03560) - 638428..638652 (+) 225 WP_003025424.1 Blp family class II bacteriocin -
  PO908_RS03580 (PO908_03565) - 638740..639060 (+) 321 WP_003037422.1 hypothetical protein -
  PO908_RS03585 (PO908_03570) - 639068..639301 (+) 234 WP_003025420.1 garvicin Q family class II bacteriocin -
  PO908_RS03590 (PO908_03575) - 639353..639643 (+) 291 WP_021001453.1 bacteriocin immunity protein -
  PO908_RS03595 (PO908_03580) - 639795..640115 (+) 321 WP_003025418.1 hypothetical protein -
  PO908_RS03600 (PO908_03585) - 640345..640575 (+) 231 WP_021001454.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 28788.23 Da        Isoelectric Point: 8.4655

>NTDB_id=782241 PO908_RS03555 WP_037590320.1 635290..636036(-) (comE/blpR) [Streptococcus anginosus strain CGMH_KH1]
MNIFILEDDLTQQYYMETIVEKIIEKHRLQYHHFEVFGKPKQLLEAISEKGSHQVFFLDIEIKTEEKKGLDVAKKIREID
PYAIIVFVTSHSELMPAAFKLQVGALDYLDKSLSKETFKKRIETALLHTENLTGKGLADDSLLFETPHTQIQVPFKDILY
IETSSRPHRLVLYTHRGRTEFTANLSDMLKKEKRFYQCHRSFVVNPANVHQVDKVNHILHFQNGATCLVSRSKIKGLTEA
IAALHRRE

Nucleotide


Download         Length: 747 bp        

>NTDB_id=782241 PO908_RS03555 WP_037590320.1 635290..636036(-) (comE/blpR) [Streptococcus anginosus strain CGMH_KH1]
ATGAATATTTTTATTTTAGAAGATGATCTTACTCAACAATATTATATGGAGACTATTGTTGAAAAAATTATCGAAAAACA
TCGTCTTCAATATCACCATTTTGAAGTTTTTGGAAAACCTAAACAATTACTAGAAGCCATATCTGAGAAAGGAAGCCATC
AGGTTTTCTTTTTGGATATTGAAATCAAAACTGAAGAAAAAAAGGGCTTAGACGTCGCCAAAAAGATACGCGAGATAGAT
CCTTATGCCATTATTGTCTTTGTAACCAGTCACTCTGAATTGATGCCGGCAGCGTTTAAACTGCAAGTCGGCGCCCTTGA
CTATCTTGACAAATCGTTATCAAAAGAAACTTTTAAAAAACGGATCGAAACTGCGCTGCTACATACTGAAAACCTAACAG
GCAAAGGCCTGGCAGACGATTCTCTTCTCTTTGAAACACCTCATACACAAATACAAGTGCCGTTTAAAGATATTCTTTAC
ATCGAAACTTCCTCTCGCCCTCACCGTTTAGTACTTTACACACATAGAGGGCGTACGGAATTTACTGCCAATCTTTCAGA
TATGTTAAAAAAAGAAAAACGGTTCTACCAATGTCATCGTTCCTTTGTTGTTAACCCAGCTAATGTCCATCAAGTGGATA
AAGTAAATCATATCCTTCACTTCCAGAATGGTGCTACTTGTCTTGTTTCTAGATCAAAAATAAAAGGGCTAACAGAAGCT
ATTGCAGCCCTGCACCGGAGGGAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

50.202

99.597

0.5
  comE/comE1 Streptococcus equinus JB1

45.992

95.565

0.44