Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PND17_RS08495 Genome accession   NZ_CP116772
Coordinates   1618353..1619588 (-) Length   411 a.a.
NCBI ID   WP_271298447.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain strain TSGB 4141     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1613353..1624588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PND17_RS08475 (PND17_08475) - 1614384..1614575 (-) 192 WP_002886272.1 DUF951 domain-containing protein -
  PND17_RS08480 (PND17_08480) dnaN 1614626..1615762 (-) 1137 WP_002948931.1 DNA polymerase III subunit beta -
  PND17_RS08485 (PND17_08485) dnaA 1615917..1617281 (-) 1365 WP_002948584.1 chromosomal replication initiator protein DnaA -
  PND17_RS08490 (PND17_08490) spo0J 1617520..1618287 (-) 768 WP_011226714.1 ParB/RepB/Spo0J family partition protein Regulator
  PND17_RS08495 (PND17_08495) htrA 1618353..1619588 (-) 1236 WP_271298447.1 S1C family serine protease Regulator
  PND17_RS08500 (PND17_08500) rlmH 1619793..1620272 (+) 480 WP_002952297.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PND17_RS08505 (PND17_08505) - 1620288..1620971 (+) 684 WP_164178359.1 YoaK family protein -
  PND17_RS08515 (PND17_08515) - 1621307..1621663 (+) 357 Protein_1661 DDE-type integrase/transposase/recombinase -
  PND17_RS08520 (PND17_08520) - 1622079..1623686 (+) 1608 WP_180476787.1 ribonuclease Y -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 42917.17 Da        Isoelectric Point: 4.6536

>NTDB_id=780069 PND17_RS08495 WP_271298447.1 1618353..1619588(-) (htrA) [Streptococcus thermophilus strain strain TSGB 4141]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDDLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=780069 PND17_RS08495 WP_271298447.1 1618353..1619588(-) (htrA) [Streptococcus thermophilus strain strain TSGB 4141]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGATCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTAGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(307-402)

Trypsin-like peptidase domain (Trypsin_2)

(118-263)

Peptidase family M50 (Peptidase_M50)

(4-406)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.538

98.054

0.603
  htrA Streptococcus gordonii str. Challis substr. CH1

57.282

100

0.574
  htrA Streptococcus mitis NCTC 12261

53.79

99.513

0.535
  htrA Streptococcus pneumoniae TIGR4

53.545

99.513

0.533
  htrA Streptococcus pneumoniae D39

53.545

99.513

0.533
  htrA Streptococcus pneumoniae Rx1

53.545

99.513

0.533
  htrA Streptococcus pneumoniae R6

53.545

99.513

0.533