Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   PHA78_RS00370 Genome accession   NZ_CP116604
Coordinates   68953..69852 (+) Length   299 a.a.
NCBI ID   WP_029184821.1    Uniprot ID   A0A2I5KL62
Organism   Streptococcus sp. HN38     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 67379..68755 68953..69852 flank 198


Gene organization within MGE regions


Location: 67379..69852
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS00370 comR 68953..69852 (+) 900 WP_029184821.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35314.20 Da        Isoelectric Point: 4.3358

>NTDB_id=778737 PHA78_RS00370 WP_029184821.1 68953..69852(+) (comR) [Streptococcus sp. HN38]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMGKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKPQFSAND
LLIIRLYLINLRMEIKQSSDFQHFLELVEKLPSQVELIESGELFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDSHLVEKLESSWREEEK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=778737 PHA78_RS00370 WP_029184821.1 68953..69852(+) (comR) [Streptococcus sp. HN38]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAACTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTACGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTACTTCGTACACCGACTTATGAAAATGAGGAATTGATGGGAAAACGGGCAGATATGATGACAGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAACCCCAATTTTCAGCCAACGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATGGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTGGAAAAGTTACCAAGCCAAGTAGAATTGATTGAATCTGGAGAATTATTTATTTTAAGAGATGTGATGCTGACGTCGA
TAGGGATTCTTGGTGAACATGAAGAATATGGCAAGATACCTCCACTTTTTGATGCTCTAGATAGAATCATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTGTATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATTGGAGACTCCCATTTAGTAGAAAAGCTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I5KL62

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

68.136

98.662

0.672
  comR Streptococcus suis 05ZYH33

68.136

98.662

0.672
  comR Streptococcus suis D9

61.538

100

0.615
  comR Streptococcus mutans UA159

42.14

100

0.421
  comR Streptococcus pyogenes MGAS8232

37.71

99.331

0.375
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.542

96.321

0.371
  comR Streptococcus pyogenes MGAS315

36.486

98.997

0.361