Detailed information NTG0777440

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PJV85_RS04400
• Genome accession: NZ_CP116457
• Coordinates: 887338..888174 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1095
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 882338..893174

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PJV85_RS04370 (PJV85_04370)	-	882892..883260 (+)	369	WP_010922310.1	hypothetical protein	-
PJV85_RS04375 (PJV85_04375)	-	883310..884221 (-)	912	WP_136273951.1	diacylglycerol/lipid kinase family protein	-
PJV85_RS04380 (PJV85_04380)	trhA	884338..884988 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
PJV85_RS04385 (PJV85_04385)	-	884985..885425 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
PJV85_RS04390 (PJV85_04390)	ylqF	885644..886492 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
PJV85_RS04395 (PJV85_04395)	-	886482..887273 (+)	792	WP_011285534.1	ribonuclease HII	-
PJV85_RS04400 (PJV85_04400)	dprA	887338..888174 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
PJV85_RS04405 (PJV85_04405)	topA	888281..890410 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
PJV85_RS04410 (PJV85_04410)	-	890485..891367 (-)	883	Protein_829	LysR family transcriptional regulator	-
PJV85_RS04415 (PJV85_04415)	-	891380..891925 (+)	546	Protein_830	PTS sugar transporter subunit IIC	-
PJV85_RS04420 (PJV85_04420)	-	891940..892932 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=777440 PJV85_RS04400 WP_010922314.1 887338..888174(+) (dprA) [Streptococcus pyogenes strain 1095]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=777440 PJV85_RS04400 WP_010922314.1 887338..888174(+) (dprA) [Streptococcus pyogenes strain 1095]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367