Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QWI19_RS20730 Genome accession   NZ_CP129123
Coordinates   4006874..4008076 (-) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis strain 6D1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4001874..4013076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QWI19_RS20705 - 4002824..4004275 (-) 1452 WP_044052405.1 HAMP domain-containing sensor histidine kinase -
  QWI19_RS20710 - 4004272..4004955 (-) 684 WP_048654834.1 response regulator transcription factor -
  QWI19_RS20715 - 4005167..4006066 (+) 900 WP_015250814.1 PepSY domain-containing protein -
  QWI19_RS20720 - 4006227..4006727 (+) 501 WP_015250813.1 PepSY domain-containing protein -
  QWI19_RS20725 - 4006724..4006853 (-) 130 Protein_4029 hypothetical protein -
  QWI19_RS20730 htrA 4006874..4008076 (-) 1203 WP_015250812.1 serine protease HtrC Regulator
  QWI19_RS20735 vicX 4008158..4008952 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  QWI19_RS20740 walI 4008974..4009816 (-) 843 WP_015250811.1 WalRK two-component regulatory system regulator WalI -
  QWI19_RS20745 walH 4009803..4011170 (-) 1368 WP_015250810.1 WalRK two-component regulatory system regulator WalH -
  QWI19_RS20750 walK 4011160..4012995 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=777084 QWI19_RS20730 WP_015250812.1 4006874..4008076(-) (htrA) [Bacillus subtilis strain 6D1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=777084 QWI19_RS20730 WP_015250812.1 4006874..4008076(-) (htrA) [Bacillus subtilis strain 6D1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGTAATGTGTCGCCCGCCGTTGTGGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATCGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378