Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   PFZ59_RS02405 Genome accession   NZ_CP116393
Coordinates   472941..473843 (-) Length   300 a.a.
NCBI ID   WP_208582736.1    Uniprot ID   -
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 471433..472725 472941..473843 flank 216


Gene organization within MGE regions


Location: 471433..473843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS02400 (PFZ59_02400) - 471469..472725 (+) 1257 WP_277697764.1 ISL3 family transposase -
  PFZ59_RS02405 (PFZ59_02405) comR 472941..473843 (-) 903 WP_208582736.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35322.38 Da        Isoelectric Point: 4.4250

>NTDB_id=777084 PFZ59_RS02405 WP_208582736.1 472941..473843(-) (comR) [Streptococcus suis strain SS/UPM/MY/F001]
MNDKEFGQRVRQLRENASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMGKRADMMTEIYDDYYDDLPEEEKIAIDAIQSTIDVFETKTAEFGQDILEDYFEQIHRKKQFSVND
LLIIQLYLINLRMEVKQSSDFQYFLELVEKFPSQVELVESGDLFILRDVMITSVGLLGQKEEFSYIPTLFEALDKIMQKT
QDFQKKPILNLLKWKYELLINKDKDAATALYEEALLFARIIGNAHLTAKLEEEWRKDSQL

Nucleotide


Download         Length: 903 bp        

>NTDB_id=777084 PFZ59_RS02405 WP_208582736.1 472941..473843(-) (comR) [Streptococcus suis strain SS/UPM/MY/F001]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAAACGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTACGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAA
TTTGATGTGCTTCGCACACCAACTTATGAAAATGAGGAATTGATGGGAAAACGGGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCCGAGGAGGAGAAAATAGCAATCGATGCTATTCAATCAACCATTGACGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAGATACATAGAAAAAAACAATTTTCAGTCAATGAT
TTGTTGATAATCCAGCTCTATTTAATCAATTTGAGAATGGAAGTTAAACAGAGTAGTGATTTCCAGTATTTTTTAGAGTT
GGTTGAAAAGTTTCCGAGCCAAGTAGAATTAGTTGAATCTGGGGATTTGTTTATTTTAAGGGATGTGATGATAACTTCTG
TTGGACTTTTGGGACAAAAGGAAGAATTTAGCTATATTCCTACACTCTTTGAAGCACTTGATAAGATAATGCAGAAGACT
CAAGATTTTCAAAAGAAACCTATTCTTAATCTGCTTAAGTGGAAATATGAGTTGTTAATAAATAAAGATAAAGATGCAGC
AACTGCCTTATATGAAGAAGCACTTCTTTTTGCAAGAATAATTGGTAATGCACACCTAACGGCTAAATTAGAAGAAGAGT
GGAGAAAAGATAGTCAATTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

66.89

99.667

0.667
  comR Streptococcus suis 05ZYH33

66.89

99.667

0.667
  comR Streptococcus suis D9

60.465

100

0.607
  comR Streptococcus mutans UA159

43.478

99.667

0.433
  comR Streptococcus pyogenes MGAS8232

40.203

98.667

0.397
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

40.345

96.667

0.39
  comR Streptococcus pyogenes MGAS315

36.242

99.333

0.36