Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QPK28_RS22175 Genome accession   NZ_CP126576
Coordinates   4255164..4256375 (-) Length   403 a.a.
NCBI ID   WP_003177958.1    Uniprot ID   -
Organism   Bacillus licheniformis strain CQMB003     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4250164..4261375
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QPK28_RS22145 rlmH 4250917..4251396 (-) 480 WP_003177946.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  QPK28_RS22150 - 4251477..4251635 (-) 159 WP_003177948.1 CxxH/CxxC protein -
  QPK28_RS22155 - 4251834..4252316 (-) 483 WP_035333986.1 DUF4234 domain-containing protein -
  QPK28_RS22160 - 4252747..4253265 (-) 519 WP_011201784.1 GNAT family N-acetyltransferase -
  QPK28_RS22165 - 4253296..4253766 (-) 471 WP_003177954.1 membrane protein -
  QPK28_RS22170 - 4254022..4254867 (-) 846 WP_061578315.1 S-adenosyl-l-methionine hydroxide adenosyltransferase family protein -
  QPK28_RS22175 htrA 4255164..4256375 (-) 1212 WP_003177958.1 trypsin-like peptidase domain-containing protein Regulator
  QPK28_RS22180 vicX 4256458..4257252 (-) 795 WP_003177960.1 MBL fold metallo-hydrolase Regulator
  QPK28_RS22185 yycI 4257267..4258115 (-) 849 WP_003177962.1 two-component system regulatory protein YycI -
  QPK28_RS22190 yycH 4258102..4259466 (-) 1365 WP_003177963.1 two-component system activity regulator YycH -
  QPK28_RS22195 walK 4259456..4261300 (-) 1845 WP_003177965.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 403 a.a.        Molecular weight: 43091.90 Da        Isoelectric Point: 5.7694

>NTDB_id=767548 QPK28_RS22175 WP_003177958.1 4255164..4256375(-) (htrA) [Bacillus licheniformis strain CQMB003]
MEFNHDEEKFVREKPVRSWRSFLFSSLVGAVIGALLTVFALPYLSQQGWLPYNLQVIEARGGQGAQQGGTVRNVSVNVNN
EVTQVVSKVSDSVVGVINIQKTGVWDGDSEAGTGSGVIYKKDGNTSHIVTNHHVIEGASQIEISLNDGTRIPAKLIGSDK
LMDLAVLQVNSNKIKAAAEFGDSDKVKTGEPVIAIGNPLGLQFSGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDA
AINPGNSGGGLFNIDGKVIGINSMKIAESAVEGIGLSIPANLAIPVIEDLETYGEVRRPYLGIEMKSLGDIASYHWQETL
KLPKNVTSGVVVMGVQPVSPAGRAGLKELDVIVEFNGDRVYDIVDLRKKLYTKNVGDKVKIKYLRGGKEKTTEVKLTRSQ
LGS

Nucleotide


Download         Length: 1212 bp        

>NTDB_id=767548 QPK28_RS22175 WP_003177958.1 4255164..4256375(-) (htrA) [Bacillus licheniformis strain CQMB003]
GTGGAGTTTAATCATGATGAGGAAAAATTCGTTCGGGAAAAGCCGGTGAGAAGTTGGAGAAGCTTTTTGTTTTCAAGCCT
GGTCGGCGCCGTCATCGGCGCTCTTTTAACAGTGTTTGCCTTGCCGTATCTCTCGCAGCAGGGATGGCTGCCGTATAATC
TGCAAGTCATCGAAGCGCGCGGCGGCCAAGGAGCACAGCAGGGCGGGACGGTCCGCAATGTATCCGTCAACGTGAATAAT
GAAGTCACGCAAGTGGTCTCTAAGGTTTCTGATTCTGTTGTCGGCGTTATCAACATCCAAAAGACAGGTGTATGGGATGG
TGACAGCGAAGCGGGAACAGGCTCGGGCGTTATTTATAAAAAGGACGGCAACACATCCCACATTGTGACAAACCACCATG
TCATTGAAGGGGCGTCCCAAATAGAAATCAGCCTGAATGACGGAACACGGATTCCGGCAAAACTGATCGGCAGCGATAAG
CTGATGGATCTGGCCGTCCTGCAAGTCAACAGCAACAAAATAAAAGCAGCTGCCGAATTTGGAGATTCTGATAAAGTGAA
GACAGGCGAGCCTGTCATCGCGATTGGAAACCCGCTCGGCCTGCAGTTTTCAGGCTCTGTTACACAAGGAATCATCTCAG
GAACCGAACGCGCTGTGCCGGTCGATTCCAACGGAGACGGACAGCCGGACTGGAACGCCGAAGTACTGCAGACGGATGCT
GCCATTAACCCGGGTAACAGCGGAGGCGGGCTGTTTAATATTGATGGAAAAGTCATCGGCATTAATTCGATGAAAATCGC
TGAATCAGCCGTCGAAGGCATCGGTCTGAGCATTCCGGCCAACCTTGCCATTCCGGTTATCGAAGATTTGGAAACGTACG
GTGAAGTGAGACGGCCGTATCTCGGAATTGAGATGAAATCACTTGGCGATATCGCAAGCTACCACTGGCAGGAAACGCTT
AAACTGCCGAAAAACGTAACATCAGGCGTAGTTGTGATGGGTGTTCAGCCGGTATCTCCTGCAGGCAGAGCCGGTCTGAA
AGAGCTCGATGTCATCGTCGAATTTAACGGTGACCGTGTTTACGATATCGTTGATCTGCGTAAAAAGCTTTACACCAAAA
ACGTCGGCGACAAGGTAAAAATCAAATACCTGCGGGGCGGAAAAGAAAAGACAACAGAAGTAAAGCTGACCCGATCCCAA
TTAGGAAGCTGA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(299-396)

Peptidase family M50 (Peptidase_M50)

(240-398)

Trypsin-like peptidase domain (Trypsin_2)

(114-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

43.799

94.045

0.412
  htrA Streptococcus mutans UA159

45.17

87.345

0.395
  htrA Streptococcus pneumoniae D39

46.847

82.63

0.387
  htrA Streptococcus pneumoniae TIGR4

46.847

82.63

0.387
  htrA Streptococcus pneumoniae R6

46.847

82.63

0.387
  htrA Streptococcus pneumoniae Rx1

46.847

82.63

0.387
  htrA Streptococcus gordonii str. Challis substr. CH1

42.693

86.6

0.37