Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   O6R09_RS04870 Genome accession   NZ_CP114883
Coordinates   937941..938615 (-) Length   224 a.a.
NCBI ID   WP_154454729.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 932941..943615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS04845 (O6R09_04845) deoC 933526..934188 (-) 663 WP_154454733.1 deoxyribose-phosphate aldolase -
  O6R09_RS04850 (O6R09_04850) - 934596..935192 (-) 597 WP_235281240.1 class I SAM-dependent methyltransferase -
  O6R09_RS04855 (O6R09_04855) coaA 935300..936220 (+) 921 WP_154454732.1 type I pantothenate kinase -
  O6R09_RS04860 (O6R09_04860) rpsT 936274..936525 (+) 252 WP_154454731.1 30S ribosomal protein S20 -
  O6R09_RS04865 (O6R09_04865) ciaH 936608..937951 (-) 1344 WP_154454730.1 sensor histidine kinase Regulator
  O6R09_RS04870 (O6R09_04870) ciaR 937941..938615 (-) 675 WP_154454729.1 response regulator transcription factor Regulator
  O6R09_RS04875 (O6R09_04875) - 938775..941315 (-) 2541 WP_154454728.1 M1 family metallopeptidase -
  O6R09_RS04880 (O6R09_04880) phoU 941480..942133 (-) 654 WP_154454727.1 phosphate signaling complex protein PhoU -
  O6R09_RS04885 (O6R09_04885) pstB 942168..942926 (-) 759 WP_154454726.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25422.15 Da        Isoelectric Point: 4.3563

>NTDB_id=767334 O6R09_RS04870 WP_154454729.1 937941..938615(-) (ciaR) [Streptococcus alactolyticus strain LGM]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGISTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKYNSNTLSYKEVTVDTATNTTTVDGKVVELLGKEFDLLVY
FLQNQNVILPKSQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTEFAKNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=767334 O6R09_RS04870 WP_154454729.1 937941..938615(-) (ciaR) [Streptococcus alactolyticus strain LGM]
ATGATTAAGATTTTGTTAGTTGAAGATGATTTGAGCTTGTCAAATTCTGTCTTTGATTTCTTGGATGATTTTGCGGATGT
GATGCAGGTTTTTGACGGTGAAGAAGGTCTTTATGAAGCTGAAAGTGGGGTCTATGACTTGATTTTGCTTGACCTTATGT
TACCTGAAAAAGACGGTTTCCAAGTGCTTAAAGAATTGCGTGAAAAAGGTATTTCGACGCCTGTTTTGATTATGACAGCG
AAAGAAAGCCTTGATGATAAGGGGCATGGTTTTGAGTTGGGAGCAGATGATTACTTGACTAAGCCTTTCTACCTTGAAGA
GTTGAAAATGCGTATTCAGGCCCTTTTGAAACGCTCTGGAAAATACAATAGCAATACCTTGTCTTACAAAGAAGTGACCG
TTGATACCGCGACAAATACCACAACTGTTGACGGAAAAGTCGTTGAATTGCTTGGTAAAGAATTTGATTTGTTGGTTTAC
TTTTTACAAAACCAAAACGTTATTTTGCCAAAATCACAAATTTTTGACCGTTTGTGGGGATTTGACAGTGATACGACCAT
TTCGGTGGTGGAAGTCTATGTGTCTAAAATACGCAAAAAATTGAAGGGAACTGAGTTTGCCAAAAACCTTCAAACACTGC
GTAGTGTGGGGTACATTCTAAAAGATGCGGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

91.928

99.554

0.915
  ciaR Streptococcus pneumoniae Rx1

88.393

100

0.884
  ciaR Streptococcus pneumoniae D39

88.393

100

0.884
  ciaR Streptococcus pneumoniae R6

88.393

100

0.884
  ciaR Streptococcus pneumoniae TIGR4

88.393

100

0.884
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.889

100

0.371
  vicR Streptococcus mutans UA159

34.764

100

0.362