Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   O6R09_RS04865 Genome accession   NZ_CP114883
Coordinates   936608..937951 (-) Length   447 a.a.
NCBI ID   WP_154454730.1    Uniprot ID   A0A6N7X2D4
Organism   Streptococcus alactolyticus strain LGM     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 931608..942951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS04840 (O6R09_04840) - 932308..933369 (-) 1062 WP_154454734.1 BMP family lipoprotein -
  O6R09_RS04845 (O6R09_04845) deoC 933526..934188 (-) 663 WP_154454733.1 deoxyribose-phosphate aldolase -
  O6R09_RS04850 (O6R09_04850) - 934596..935192 (-) 597 WP_235281240.1 class I SAM-dependent methyltransferase -
  O6R09_RS04855 (O6R09_04855) coaA 935300..936220 (+) 921 WP_154454732.1 type I pantothenate kinase -
  O6R09_RS04860 (O6R09_04860) rpsT 936274..936525 (+) 252 WP_154454731.1 30S ribosomal protein S20 -
  O6R09_RS04865 (O6R09_04865) ciaH 936608..937951 (-) 1344 WP_154454730.1 sensor histidine kinase Regulator
  O6R09_RS04870 (O6R09_04870) ciaR 937941..938615 (-) 675 WP_154454729.1 response regulator transcription factor Regulator
  O6R09_RS04875 (O6R09_04875) - 938775..941315 (-) 2541 WP_154454728.1 M1 family metallopeptidase -
  O6R09_RS04880 (O6R09_04880) phoU 941480..942133 (-) 654 WP_154454727.1 phosphate signaling complex protein PhoU -
  O6R09_RS04885 (O6R09_04885) pstB 942168..942926 (-) 759 WP_154454726.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 50946.27 Da        Isoelectric Point: 6.2546

>NTDB_id=767333 O6R09_RS04865 WP_154454730.1 936608..937951(-) (ciaH) [Streptococcus alactolyticus strain LGM]
MRNKWSKKLLSGTTSSHFFHFFAVFTGIFIVMTVIILQIMRFGLYSTVDTNLQNAAYNANDYVARTMKRSDSLQVDDSDY
ESFFAGENGSKLKSALNGETLTNVSVLLYDKKGKILNALDAFLQFGALSYSFDEDSIGEIKEEKIKTIFGQNEKYHVLTV
KVDDADYPAIKYATFLISVRQLDEANERYVTITITVMVIFWMISILASIYLANWTRKPILESYEKQKAFVENASHELRTP
LAVLQNRLEGLFRRPNDTILDNSESIAASLDEVRNMRFLITNLLNLARRDDVLKVDLEMIQPTMFDEVFENYSLIAEESN
RIFIGQNLATHPIKSDRVLLKQLMTILFDNAIKYTDEDGVVEFTVKTTERHTIITVADNGIGISDSDKLKIFDRFYRVDK
SRTRQKGGFGLGLSLAQQIVDALKGTITVKDNTPKGTIFEVCFNHHH

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=767333 O6R09_RS04865 WP_154454730.1 936608..937951(-) (ciaH) [Streptococcus alactolyticus strain LGM]
ATGCGGAATAAGTGGTCTAAGAAATTACTATCAGGGACAACCTCTTCGCATTTCTTCCATTTCTTCGCGGTCTTTACAGG
TATTTTCATCGTCATGACTGTTATTATCTTGCAAATCATGCGTTTTGGTTTGTATTCGACAGTGGATACCAATTTGCAAA
ATGCTGCTTATAATGCTAATGATTATGTCGCTCGGACGATGAAGCGCAGCGATTCTTTGCAGGTTGATGATTCGGACTAT
GAATCCTTTTTTGCGGGTGAAAATGGCAGCAAACTCAAATCAGCCCTCAACGGCGAAACGCTAACCAATGTGAGTGTTCT
TTTGTACGATAAAAAGGGCAAGATTTTAAATGCCTTGGACGCCTTTCTCCAATTTGGTGCTTTATCTTACAGCTTTGATG
AGGATAGCATTGGGGAGATTAAAGAGGAAAAAATCAAAACCATTTTCGGGCAAAATGAAAAATACCATGTGCTGACGGTC
AAAGTCGATGATGCGGATTATCCAGCGATTAAGTACGCAACTTTTTTGATTAGCGTGCGGCAGCTGGACGAAGCTAATGA
ACGTTACGTGACCATTACGATCACAGTCATGGTGATTTTCTGGATGATTTCCATTTTGGCGAGCATCTACCTTGCCAATT
GGACGCGTAAGCCGATTTTGGAAAGTTATGAAAAGCAAAAAGCCTTCGTGGAAAATGCCAGTCACGAATTGCGGACGCCA
TTAGCTGTTTTGCAAAACCGTTTGGAAGGTTTGTTTAGAAGACCTAATGACACGATTTTAGATAATAGCGAAAGCATTGC
GGCTAGCCTTGACGAAGTCCGTAATATGCGCTTTTTGATTACCAATTTGCTCAATTTGGCTCGGCGAGATGATGTCTTGA
AGGTTGATTTAGAAATGATTCAGCCAACCATGTTCGATGAAGTCTTTGAAAATTACAGCCTCATTGCCGAGGAGAGTAAT
CGTATCTTTATTGGGCAAAATCTAGCTACCCACCCGATCAAATCAGACCGTGTCTTGCTCAAACAATTGATGACCATCTT
ATTTGATAATGCCATTAAATACACGGATGAAGATGGCGTGGTTGAATTTACCGTTAAAACAACGGAAAGACACACCATTA
TCACGGTTGCGGACAATGGTATCGGTATTAGTGATAGCGATAAGCTGAAGATTTTTGACCGATTCTACCGAGTGGACAAG
TCAAGAACGCGTCAAAAGGGTGGATTTGGTTTAGGCTTGTCCCTAGCTCAACAAATCGTGGACGCCCTAAAGGGAACCAT
TACAGTCAAAGACAATACACCTAAAGGAACAATTTTTGAAGTGTGTTTTAACCACCATCATTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-290)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N7X2D4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.451

95.302

0.557
  ciaH Streptococcus pneumoniae Rx1

50.585

95.526

0.483
  ciaH Streptococcus pneumoniae D39

50.585

95.526

0.483
  ciaH Streptococcus pneumoniae R6

50.585

95.526

0.483
  ciaH Streptococcus pneumoniae TIGR4

50.585

95.526

0.483