Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   O6R09_RS00350 Genome accession   NZ_CP114883
Coordinates   51337..52275 (+) Length   312 a.a.
NCBI ID   WP_269725856.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 52280..53584 51337..52275 flank 5


Gene organization within MGE regions


Location: 51337..53584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS00350 (O6R09_00350) comR 51337..52275 (+) 939 WP_269725856.1 helix-turn-helix domain-containing protein Regulator
  O6R09_RS00355 (O6R09_00355) - 52280..53536 (-) 1257 WP_269725514.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 36023.14 Da        Isoelectric Point: 4.5693

>NTDB_id=767302 O6R09_RS00350 WP_269725856.1 51337..52275(+) (comR) [Streptococcus alactolyticus strain LGM]
MMKAFGEKVRQLREERGISREAFCGDETELSIRQLYRVETGQSIPTLNKVTYIAQILGVSIGELTDGKTFELPARYKELK
YLLLRTPTYGDQERLQKKSHYFDEIAEQYYEVIPEEERLMMDCLQSKIDVHFSDDVNFGEGILHEYFDQVLKKQVFSLND
LIVIDLYLACLASAPVLEGIYSLDLYKTLMERLLDQDIADPETALILNNVLLNNVDLAFRFQKDTFVEAIMSKSSDIMTA
IHDFQKRPILSLVEWKYQLHFKNDLATAQESYTKAILFASLIGDTHLEEQLVTEWQKDTQNYPGSLSTVVGR

Nucleotide


Download         Length: 939 bp        

>NTDB_id=767302 O6R09_RS00350 WP_269725856.1 51337..52275(+) (comR) [Streptococcus alactolyticus strain LGM]
ATTATGAAAGCATTTGGGGAAAAGGTGCGCCAGTTAAGAGAAGAGCGTGGGATTTCACGTGAGGCTTTTTGTGGCGATGA
AACGGAATTGTCTATTCGGCAGTTGTATCGGGTTGAAACAGGGCAGTCCATTCCAACACTAAACAAGGTAACCTATATCG
CGCAGATTTTGGGAGTGAGCATTGGTGAGCTAACCGATGGCAAGACCTTTGAACTTCCAGCTAGATACAAGGAATTAAAG
TATTTGCTGCTGAGAACACCGACTTATGGGGACCAAGAACGCCTGCAAAAAAAGAGCCATTATTTTGATGAAATTGCGGA
GCAGTATTACGAAGTCATTCCAGAAGAAGAACGCTTGATGATGGATTGCTTGCAGTCTAAGATAGATGTGCACTTCAGCG
ATGATGTTAATTTTGGAGAGGGCATTTTGCACGAGTATTTTGACCAAGTTCTAAAAAAGCAGGTTTTTTCCTTAAATGAC
CTGATTGTGATTGATTTGTACTTGGCTTGTTTGGCCTCAGCTCCCGTTTTAGAAGGCATTTACAGTTTGGATTTGTATAA
GACTTTGATGGAACGCTTGTTGGACCAAGACATTGCTGACCCTGAAACGGCACTGATTTTGAATAATGTTTTGCTAAATA
ACGTTGACTTGGCTTTTCGTTTTCAAAAGGACACTTTTGTGGAGGCTATCATGTCAAAAAGCAGTGACATCATGACGGCG
ATTCACGATTTTCAAAAACGCCCCATTTTAAGCTTGGTAGAGTGGAAATATCAGCTGCATTTCAAAAATGATTTGGCTAC
TGCACAAGAATCTTATACCAAAGCCATTTTATTTGCCAGTTTGATAGGAGATACCCATCTAGAAGAGCAGTTGGTCACGG
AATGGCAAAAGGATACCCAAAACTATCCCGGCTCTTTGTCAACTGTAGTGGGTAGATGA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(4-63)

ComR tetratricopeptide (ComR_TPR)

(73-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

66.551

91.987

0.612
  comR Streptococcus mutans UA159

53.974

96.795

0.522
  comR Streptococcus pyogenes MGAS8232

46.053

97.436

0.449
  comR Streptococcus pyogenes MGAS315

44.816

95.833

0.429
  comR Streptococcus suis D9

39.867

96.474

0.385
  comR Streptococcus suis P1/7

37.793

95.833

0.362
  comR Streptococcus suis 05ZYH33

37.793

95.833

0.362