Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QNK06_RS22030 Genome accession   NZ_CP126097
Coordinates   4171100..4172302 (-) Length   400 a.a.
NCBI ID   WP_283933971.1    Uniprot ID   -
Organism   Bacillus subtilis strain KF24     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4166100..4177302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QNK06_RS22005 (QNK06_22005) rocE 4166334..4167737 (-) 1404 WP_021481073.1 amino acid permease -
  QNK06_RS22010 (QNK06_22010) rocD 4167960..4169165 (-) 1206 WP_172861696.1 ornithine aminotransferase -
  QNK06_RS22015 (QNK06_22015) rocR 4169406..4170791 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  QNK06_RS22020 (QNK06_22020) - 4170773..4170931 (-) 159 Protein_4289 ATP-binding protein -
  QNK06_RS22025 (QNK06_22025) - 4170953..4171080 (-) 128 Protein_4290 hypothetical protein -
  QNK06_RS22030 (QNK06_22030) htrA 4171100..4172302 (-) 1203 WP_283933971.1 serine protease HtrC Regulator
  QNK06_RS22035 (QNK06_22035) vicX 4172384..4173178 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  QNK06_RS22040 (QNK06_22040) walI 4173200..4174042 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  QNK06_RS22045 (QNK06_22045) walH 4174029..4175396 (-) 1368 WP_159377178.1 WalRK two-component regulatory system regulator WalH -
  QNK06_RS22050 (QNK06_22050) walK 4175386..4177221 (-) 1836 WP_106610980.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42720.46 Da        Isoelectric Point: 5.1904

>NTDB_id=767039 QNK06_RS22030 WP_283933971.1 4171100..4172302(-) (htrA) [Bacillus subtilis strain KF24]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNTGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=767039 QNK06_RS22030 WP_283933971.1 4171100..4172302(-) (htrA) [Bacillus subtilis strain KF24]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACGGGCG
CTTTAGATCAGCAGCAGAACAACACCGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCGGTCACCAAG
ATTGTCAGCAATGTGTCACCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGTTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCTGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCCGT
AGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGGATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTTACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCTGGGAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(183-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

46.364

82.5

0.383
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373