Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   OIY87_RS05995 Genome accession   NZ_CP113954
Coordinates   1182381..1183223 (-) Length   280 a.a.
NCBI ID   WP_064593000.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain XH2168     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1169003..1182244 1182381..1183223 flank 137


Gene organization within MGE regions


Location: 1169003..1183223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OIY87_RS05875 (OIY87_07190) - 1169003..1169485 (-) 483 WP_269724811.1 hypothetical protein -
  OIY87_RS05880 (OIY87_07195) - 1169502..1170290 (-) 789 WP_269724812.1 DNA/RNA non-specific endonuclease -
  OIY87_RS05885 (OIY87_07200) - 1170293..1170637 (-) 345 WP_039671381.1 hypothetical protein -
  OIY87_RS05890 (OIY87_07205) - 1170630..1170968 (-) 339 WP_269724813.1 hypothetical protein -
  OIY87_RS05895 (OIY87_07210) - 1171387..1171671 (-) 285 WP_014620294.1 hypothetical protein -
  OIY87_RS05900 (OIY87_07215) - 1171847..1172659 (-) 813 WP_269724814.1 hypothetical protein -
  OIY87_RS05905 (OIY87_07220) - 1172697..1173710 (-) 1014 WP_269724815.1 hypothetical protein -
  OIY87_RS05910 (OIY87_07225) - 1173894..1174232 (-) 339 WP_269724816.1 hypothetical protein -
  OIY87_RS05915 (OIY87_07230) - 1174251..1174685 (-) 435 WP_269724817.1 hypothetical protein -
  OIY87_RS05920 (OIY87_07235) - 1174695..1175048 (-) 354 WP_269724818.1 hypothetical protein -
  OIY87_RS05925 (OIY87_07240) - 1175045..1175491 (-) 447 Protein_1104 hypothetical protein -
  OIY87_RS05930 (OIY87_07245) - 1175716..1175910 (-) 195 WP_043910913.1 hypothetical protein -
  OIY87_RS05935 (OIY87_07250) - 1175903..1176331 (-) 429 WP_420067736.1 thioredoxin family protein -
  OIY87_RS05940 (OIY87_07255) - 1176324..1176740 (-) 417 WP_039671391.1 hypothetical protein -
  OIY87_RS05945 (OIY87_07260) - 1176754..1176909 (-) 156 WP_014620303.1 hypothetical protein -
  OIY87_RS05950 (OIY87_07265) - 1176921..1177124 (-) 204 WP_074656606.1 hypothetical protein -
  OIY87_RS05955 (OIY87_07270) - 1177135..1177308 (-) 174 WP_269724820.1 hypothetical protein -
  OIY87_RS05960 (OIY87_07275) - 1177457..1178959 (-) 1503 WP_269724821.1 primase C-terminal domain-containing protein -
  OIY87_RS05965 (OIY87_07280) - 1178956..1179309 (-) 354 WP_196756552.1 hypothetical protein -
  OIY87_RS05970 (OIY87_07285) - 1179364..1179519 (-) 156 WP_172454532.1 hypothetical protein -
  OIY87_RS05975 (OIY87_07290) - 1179534..1180271 (-) 738 WP_269724822.1 hypothetical protein -
  OIY87_RS05980 (OIY87_07295) - 1180295..1180789 (-) 495 WP_014620309.1 hypothetical protein -
  OIY87_RS05985 (OIY87_07300) dcm 1180803..1181987 (-) 1185 WP_269724823.1 DNA (cytosine-5-)-methyltransferase -
  OIY87_RS05990 (OIY87_07305) - 1182020..1182244 (-) 225 WP_269724824.1 hypothetical protein -
  OIY87_RS05995 (OIY87_07310) dprA 1182381..1183223 (-) 843 WP_064593000.1 DNA-processing protein DprA Machinery gene

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30929.95 Da        Isoelectric Point: 8.5553

>NTDB_id=763826 OIY87_RS05995 WP_064593000.1 1182381..1183223(-) (dprA) [Streptococcus gallolyticus strain XH2168]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDTKELRKEFNCFPSVSILDDEYP
LELKHCYNPPVLLFYQGNLELLNRQKMAVVGARTASASGTKSVQKIVKELGNHFVIVSGLARGIDTSAHLSALKNGGASI
AVIGCGLDVYYPKENKQLQAYMAKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVTSGLDILSEYQI

Nucleotide


Download         Length: 843 bp        

>NTDB_id=763826 OIY87_RS05995 WP_064593000.1 1182381..1183223(-) (dprA) [Streptococcus gallolyticus strain XH2168]
ATGAATAATTTTGAATTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAATATTTTAGCTATTTTAGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTGGACACCAAAGAATTGCGCAAAGAATTTAATTGTTTTCCTAGTGTTTCCATACTAGATGACGAATACCCA
TTAGAACTCAAACATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAATTACTCAATCGCCAAAAAAT
GGCAGTAGTAGGAGCAAGAACAGCATCAGCATCAGGGACAAAATCCGTACAGAAAATTGTCAAAGAACTCGGGAATCATT
TTGTTATCGTTAGTGGGTTGGCGCGTGGCATTGATACCAGTGCGCATTTATCAGCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGCGGACTGGACGTTTATTATCCCAAAGAAAATAAGCAGTTGCAGGCGTACATGGCTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGTTTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGCGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGAAAATCTGATGGCTGTCATCATTTGATAAAAGAGGGCGCAAAATG
CGTCACATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

74.101

99.286

0.736
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.929

100

0.639
  dprA/cilB/dalA Streptococcus mitis SK321

63.929

100

0.639
  dprA Lactococcus lactis subsp. cremoris KW2

62.23

99.286

0.618
  dprA Haemophilus influenzae Rd KW20

38.636

94.286

0.364