Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   OTB22_RS08055 Genome accession   NZ_CP113267
Coordinates   1585846..1587489 (+) Length   547 a.a.
NCBI ID   WP_317657564.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1580846..1592489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS08010 (OTB22_08015) blpN 1581187..1581390 (-) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  OTB22_RS08015 (OTB22_08020) blpM 1581406..1581660 (-) 255 WP_000379877.1 two-peptide bacteriocin subunit BlpM -
  OTB22_RS08020 (OTB22_08025) - 1581810..1582615 (-) 806 Protein_1596 IS5 family transposase -
  OTB22_RS08025 (OTB22_08030) - 1582818..1583222 (-) 405 WP_000846944.1 hypothetical protein -
  OTB22_RS08030 (OTB22_08035) - 1583219..1583383 (-) 165 WP_000727118.1 hypothetical protein -
  OTB22_RS08035 (OTB22_08040) - 1583680..1583799 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  OTB22_RS08040 (OTB22_08045) blpU 1583802..1584032 (-) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  OTB22_RS08045 (OTB22_08050) blpJ 1584101..1584370 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  OTB22_RS08050 (OTB22_08055) blpI 1584837..1585034 (-) 198 WP_001093261.1 bacteriocin-like peptide BlpI -
  OTB22_RS11095 comA/nlmT 1585332..1585919 (+) 588 WP_317657537.1 cysteine peptidase family C39 domain-containing protein Regulator
  OTB22_RS08055 (OTB22_08060) comA/nlmT 1585846..1587489 (+) 1644 WP_317657564.1 peptide cleavage/export ABC transporter Regulator
  OTB22_RS08060 (OTB22_08065) - 1587500..1588861 (+) 1362 Protein_1605 bacteriocin secretion accessory protein -
  OTB22_RS08065 (OTB22_08070) blpC 1588918..1589046 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  OTB22_RS08070 (OTB22_08075) - 1589117..1590457 (-) 1341 WP_001017646.1 sensor histidine kinase -
  OTB22_RS08075 (OTB22_08080) comE/blpR 1590471..1591208 (-) 738 WP_219569151.1 response regulator transcription factor Regulator
  OTB22_RS08080 (OTB22_08085) - 1591213..1591551 (-) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  OTB22_RS08085 (OTB22_08090) - 1591828..1592157 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61673.60 Da        Isoelectric Point: 6.5101

>NTDB_id=761487 OTB22_RS08055 WP_317657564.1 1585846..1587489(+) (comA/nlmT) [Streptococcus pneumoniae strain BC2]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSG
LDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=761487 OTB22_RS08055 WP_317657564.1 1585846..1587489(+) (comA/nlmT) [Streptococcus pneumoniae strain BC2]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAGTACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTGGCACAAA
ACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTTGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTT
AATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAAAGCTTATGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-268)

ABC transporter (ABC_tran)

(330-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.711

99.817

0.726
  comA Streptococcus pneumoniae Rx1

67.459

100

0.675
  comA Streptococcus pneumoniae D39

67.459

100

0.675
  comA Streptococcus pneumoniae R6

67.459

100

0.675
  comA Streptococcus mitis NCTC 12261

67.459

100

0.675
  comA Streptococcus pneumoniae TIGR4

67.093

100

0.671
  comA Streptococcus gordonii str. Challis substr. CH1

66.788

100

0.669
  comA Streptococcus mitis SK321

66.91

100

0.669