Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   OTU47_RS12065 Genome accession   NZ_CP113115
Coordinates   2193419..2193880 (+) Length   153 a.a.
NCBI ID   WP_309543754.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2189347..2195086 2193419..2193880 within 0


Gene organization within MGE regions


Location: 2189347..2195086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU47_RS11465 (OTU47_11465) - 2189347..2190152 (-) 806 Protein_2227 IS5 family transposase -
  OTU47_RS11470 (OTU47_11470) - 2190355..2190759 (-) 405 WP_000846944.1 hypothetical protein -
  OTU47_RS11475 (OTU47_11475) - 2190756..2190920 (-) 165 WP_000727118.1 hypothetical protein -
  OTU47_RS11480 (OTU47_11480) - 2191219..2191338 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  OTU47_RS11485 (OTU47_11485) blpU 2191341..2191571 (-) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  OTU47_RS11490 (OTU47_11490) blpJ 2191640..2191909 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  OTU47_RS11495 (OTU47_11495) blpI 2192376..2192573 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  OTU47_RS12060 comA/nlmT 2192887..2193474 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  OTU47_RS12065 comA/nlmT 2193419..2193880 (+) 462 WP_309543754.1 ABC transporter transmembrane domain-containing protein Regulator
  OTU47_RS11505 (OTU47_11505) - 2194133..2195086 (+) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -

Sequence

Protein


Download         Length: 153 a.a.        Molecular weight: 17224.55 Da        Isoelectric Point: 5.7319

>NTDB_id=760464 OTU47_RS12065 WP_309543754.1 2193419..2193880(+) (comA/nlmT) [Streptococcus pneumoniae strain NP2]
MVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSF
FATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPF

Nucleotide


Download         Length: 462 bp        

>NTDB_id=760464 OTU47_RS12065 WP_309543754.1 2193419..2193880(+) (comA/nlmT) [Streptococcus pneumoniae strain NP2]
TTGGTCACTATTATCAATATCGGTGGTTCTTATTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATC
AACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCTTTTCCAGAGATTATCTCC
TAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTC
TTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCAT
TCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGAGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCC
TTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTTTGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(3-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

75.817

100

0.758
  comA Streptococcus mitis SK321

72.549

100

0.725
  comA Streptococcus pneumoniae Rx1

72.549

100

0.725
  comA Streptococcus pneumoniae D39

72.549

100

0.725
  comA Streptococcus pneumoniae R6

72.549

100

0.725
  comA Streptococcus mitis NCTC 12261

72.549

100

0.725
  comA Streptococcus pneumoniae TIGR4

71.895

100

0.719
  comA Streptococcus gordonii str. Challis substr. CH1

70.588

100

0.706