Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   UKS_RS05810 Genome accession   NZ_AP021887
Coordinates   1132527..1133234 (-) Length   235 a.a.
NCBI ID   WP_049497334.1    Uniprot ID   -
Organism   Streptococcus sp. 116-D4     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1127527..1138234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UKS_RS05790 (UKS_11090) - 1128163..1129881 (+) 1719 WP_156012158.1 phospho-sugar mutase -
  UKS_RS05795 (UKS_11100) - 1129993..1130340 (+) 348 WP_156012159.1 thioredoxin -
  UKS_RS05800 (UKS_11110) vicX 1130374..1131183 (-) 810 WP_156012160.1 MBL fold metallo-hydrolase Regulator
  UKS_RS05805 (UKS_11120) micB 1131185..1132534 (-) 1350 WP_156012161.1 cell wall metabolism sensor histidine kinase VicK Regulator
  UKS_RS05810 (UKS_11130) micA 1132527..1133234 (-) 708 WP_049497334.1 response regulator YycF Regulator
  UKS_RS05815 (UKS_11140) mutY 1133290..1134465 (-) 1176 WP_156012162.1 A/G-specific adenine glycosylase -
  UKS_RS05820 (UKS_11150) pta 1134744..1135718 (-) 975 WP_049497328.1 phosphate acetyltransferase -
  UKS_RS05825 (UKS_11160) - 1135763..1136659 (-) 897 WP_156012163.1 RluA family pseudouridine synthase -
  UKS_RS05830 (UKS_11170) - 1136656..1137474 (-) 819 WP_156012164.1 NAD kinase -
  UKS_RS05835 (UKS_11180) - 1137458..1138129 (-) 672 WP_156012165.1 GTP pyrophosphokinase family protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27121.07 Da        Isoelectric Point: 4.9002

>NTDB_id=75361 UKS_RS05810 WP_049497334.1 1132527..1133234(-) (micA) [Streptococcus sp. 116-D4]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEKYEAEQPDIIILDLMLPEIDGLEVAKTIRKSSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDNQESDEKKIQPLKIGDLEIVPDAYVAKKYGKELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=75361 UKS_RS05810 WP_049497334.1 1132527..1133234(-) (micA) [Streptococcus sp. 116-D4]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGTTAGAGAAATATGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACTATTCGCAAGTCAAGTAGTGTGCCTATTATCATGCTGTCGGCT
AAAGATAGCGAATTTGACAAGGTTATCGGTTTGGAACTTGGAGCAGATGACTATGTGACAAAACCTTTCTCAAATCGTGA
ACTGCAGGCGCGTGTTAAAGCTCTTCTTCGTCGCACGGACTTGGTTTCTGTAGATAACCAAGAATCTGATGAAAAGAAAA
TCCAACCCTTGAAAATTGGGGACTTGGAGATTGTGCCAGATGCCTATGTAGCTAAAAAATACGGTAAAGAACTAGACTTA
ACCCACCGTGAATTTGAGCTCTTGTACCACTTGGCTTCTCATATTGGTCAAGTGATTACGCGTGAACACTTGCTTGAAAC
TGTCTGGGGTTATGATTATTTTGGAGATGTTCGGACTGTTGACGTAACTATTAGACGTTTGCGTGAGAAGATTGAAGACA
CACCAAGTAGACCTGAATACATCCTAACTCGTCGTGGAGTAGGATATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

91.88

99.574

0.915
  vicR Streptococcus mutans UA159

78.723

100

0.787
  covR Streptococcus salivarius strain HSISS4

45.259

98.723

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.156

98.298

0.434

Multiple sequence alignment