Detailed information NTG0075341

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: UKS_RS01820
• Genome accession: NZ_AP021887
• Coordinates: 355395..357548 (-)
• Length: 717 a.a.
• NCBI ID: WP_156011573.1
• Uniprot ID: -
• Organism: Streptococcus sp. 116-D4
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 350395..362548

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UKS_RS01790 (UKS_03250)	-	350728..351057 (-)	330	WP_156011567.1	helicase BlpT	-
UKS_RS01795 (UKS_03260)	-	351333..351671 (+)	339	WP_033684769.1	LytTR family DNA-binding domain-containing protein	-
UKS_RS01800 (UKS_03270)	comE/blpR	351676..352422 (+)	747	WP_064276246.1	response regulator transcription factor	Regulator
UKS_RS01805	-	352427..353767 (+)	1341	WP_156011569.1	sensor histidine kinase	-
UKS_RS01810 (UKS_03290)	blpC	353811..353966 (-)	156	WP_064276248.1	quorum-sensing system pheromone BlpC	-
UKS_RS01815 (UKS_03300)	-	354023..355384 (-)	1362	WP_156011571.1	bacteriocin secretion accessory protein	-
UKS_RS01820 (UKS_03310)	comA/nlmT	355395..357548 (-)	2154	WP_156011573.1	peptide cleavage/export ABC transporter BlpA	Regulator
UKS_RS01825 (UKS_03320)	-	357831..358067 (+)	237	WP_033684811.1	Blp family class II bacteriocin	-
UKS_RS01830 (UKS_03330)	-	358087..358491 (+)	405	WP_156011574.1	immunity protein	-
UKS_RS01835 (UKS_03340)	-	358656..359693 (+)	1038	WP_156011576.1	thioredoxin domain-containing protein	-
UKS_RS01840 (UKS_03350)	-	360003..360236 (+)	234	WP_156011578.1	bacteriocin class II family protein	-
UKS_RS01845 (UKS_03360)	-	360268..360957 (+)	690	WP_156011580.1	CPBP family intramembrane glutamic endopeptidase	-
UKS_RS01850 (UKS_03370)	blpZ	360999..361232 (+)	234	WP_156011582.1	immunity protein BlpZ	-
UKS_RS01855	-	361379..361990 (+)	612	WP_156011584.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80770.87 Da
• Isoelectric Point: 8.5818

>NTDB_id=75341 UKS_RS01820 WP_156011573.1 355395..357548(-) (comA/nlmT) [Streptococcus sp. 116-D4]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAANEIGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMGFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSNKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFKVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMSLTNKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=75341 UKS_RS01820 WP_156011573.1 355395..357548(-) (comA/nlmT) [Streptococcus sp. 116-D4]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCAAATGAAATAGGATTTGAAACAAGACCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCTAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATCGTTCTCTCAAGCTTATTGGTCACTATTATCAATATCGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TTACCTATATCCTCCAACAAGTCATGGGCTTCTCCAGAGATTATCTCCTAACTGTTCTGAGTCAGAGATTAAGTATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGTGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAGTATTCTATTTTACAAACGAGTTTAAAACAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCTAATAAGATTTCTATCGGTCAACTGATTACTTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTAAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTCAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCTCAACAAGCCTATATCTTTAATGGATCTATATTGGAAAATTTAACCTTGGGTGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTCTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCTCTAAC
TAATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGATCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.308	99.721	0.721
comA	Streptococcus mitis NCTC 12261	66.62	99.442	0.662
comA	Streptococcus mitis SK321	66.059	99.442	0.657
comA	Streptococcus pneumoniae Rx1	66.059	99.442	0.657
comA	Streptococcus pneumoniae D39	66.059	99.442	0.657
comA	Streptococcus pneumoniae R6	66.059	99.442	0.657
comA	Streptococcus pneumoniae TIGR4	65.778	99.442	0.654
comA	Streptococcus gordonii str. Challis substr. CH1	65.181	100	0.653