Detailed information NTG0075318

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: UKS_RS00300
• Genome accession: NZ_AP021887
• Coordinates: 55469..57622 (+)
• Length: 717 a.a.
• NCBI ID: WP_156011329.1
• Uniprot ID: -
• Organism: Streptococcus sp. 116-D4
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 50469..62622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UKS_RS00255 (UKS_00470)	-	51262..52194 (+)	933	WP_232049744.1	GHKL domain-containing protein	-
UKS_RS00260 (UKS_00480)	-	52191..52922 (+)	732	WP_049497052.1	response regulator transcription factor	-
UKS_RS00265 (UKS_00490)	-	53372..53569 (+)	198	WP_049497050.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
UKS_RS00275 (UKS_00510)	-	53783..53938 (+)	156	WP_049497045.1	smi_0061 family bacteriocin-like peptide	-
UKS_RS09765	-	53942..54145 (+)	204	WP_080977092.1	bacteriocin immunity protein	-
UKS_RS00285 (UKS_00520)	-	54225..54407 (+)	183	WP_049497042.1	hypothetical protein	-
UKS_RS00290 (UKS_00530)	-	54460..54633 (+)	174	WP_000180829.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
UKS_RS00295 (UKS_00540)	-	54757..54909 (+)	153	WP_001180498.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
UKS_RS09685 (UKS_00550)	-	54934..55089 (+)	156	WP_173020424.1	hypothetical protein	-
UKS_RS00300 (UKS_00560)	comA	55469..57622 (+)	2154	WP_156011329.1	peptide cleavage/export ABC transporter ComA	Regulator
UKS_RS00305 (UKS_00570)	comB	57635..58984 (+)	1350	WP_156011330.1	competence pheromone export protein ComB	Regulator
UKS_RS00310 (UKS_00580)	purC	59154..59861 (+)	708	WP_173020425.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80278.28 Da
• Isoelectric Point: 6.3361

>NTDB_id=75318 UKS_RS00300 WP_156011329.1 55469..57622(+) (comA) [Streptococcus sp. 116-D4]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFSYSRAESQQKALKKVAHL
LLNVGILWMGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGEMTFKQVHYKYGYGRDVLSDINLTIPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIIDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGNHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=75318 UKS_RS00300 WP_156011329.1 55469..57622(+) (comA) [Streptococcus sp. 116-D4]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAGGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGCTATTATTCTTTGGCTCACTTGCGAGAATTGGCCAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATTGGCTTTGAGACGCGAGCAATTAAGGCGGATATGACGCTATTTGACTTGCCAGATTTG
ACTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGATAG
CATTCATATTGCCGATCCAGATCCTGGGGTGAAATTGACCAAACTGCCACGTGAGCGTTTTGCGGAAGAATGGACAGGAG
TGACTCTTTTTATGGCACCTAGTCCAGACTACAAGCCTCATAAGGATCAAAAGAATGGTCTGCTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAACATCGTCCTAGCGACACTTTTGGTGACCCTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACCTTGGGGATTATTTCTATTGGGCTGGTGA
TTGTTTATATTCTCCAGCAGATCTTGTCTTACGCTCAGGAGTATCTCTTGCTTGTTTTGGGGCAACGCCTGTCGATTGAC
GTGATTTTATCCTATATCAAGCATGTTTTTCACCTGCCTATGTCCTTTTTTGCGACACGCAGGACAGGGGAAATCGTGTC
TCGTTTTACAGATGCTAATAGTATCATCGATGCGCTGGCTTCGACCATTCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCTCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCGCTTCCTATCTATACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAACGGTATTGAGACGATCAAGTCTTTGACCAGTGAAAGTCAACGTTACCAAAAGATTGACAAGGAAT
TTGTGGATTATCTGAAAAAATCCTTTTCCTATAGTCGGGCAGAGAGTCAGCAAAAGGCTTTGAAAAAAGTAGCACATCTC
TTGCTCAATGTCGGTATTCTCTGGATGGGGGCTATTCTGGTTATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACCAATCCTTTGGAAAATATCATCAACCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTTTGAATGAGGTTTATCTGGTAGCTTCTGAGTTTGAGGAGAAGAAAACGGTTGAGGATTTGAGCTTGATG
AAGGGAGAGATGACCTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGATGTCTTGTCGGATATCAATCTGACTAT
TCCGCAGGGTTCTAAGGTGGCTTTTGTAGGGATTTCAGGGTCAGGTAAGACGACCTTGGCCAAGATGATGGTTAATTTTT
ACGACCCTAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAGGCTCTACGTCAGTACATC
AACTATTTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCCAAGGAAGGGACGAC
TCAGGAGGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGAGAGGATATCGAGCGGATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGGGCAGGGATCTCAGGTGGTCAACGTCAGAGAATTGCTTTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCGACCAGCAGTTTGGATATTTTGACAGAGAAGAGGATTATCGATAATCTCATGGCTTT
AGACAAGACCTTGATTTTCATTGCCCACCGCTTGACCATTGCTGAGCGGACAGAGAAGGTTGTTGTCTTGGATCAAGGAA
AGATTGTCGAAGAAGGAAATCATGCTGATTTGCTTGCACAGGGTGGTTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	98.884	100	0.989
comA	Streptococcus mitis SK321	98.605	100	0.986
comA	Streptococcus pneumoniae Rx1	98.466	100	0.985
comA	Streptococcus pneumoniae D39	98.466	100	0.985
comA	Streptococcus pneumoniae R6	98.466	100	0.985
comA	Streptococcus pneumoniae TIGR4	98.047	100	0.98
comA	Streptococcus gordonii str. Challis substr. CH1	80.893	100	0.809
comA/nlmT	Streptococcus mutans UA159	65.272	100	0.653