Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   OHM48_RS04720 Genome accession   NZ_CP109942
Coordinates   951752..952594 (-) Length   280 a.a.
NCBI ID   WP_012775129.1    Uniprot ID   -
Organism   Streptococcus suis strain ID35541     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 946752..957594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHM48_RS04695 (OHM48_04695) - 946888..947706 (-) 819 WP_024401260.1 replication initiator protein A -
  OHM48_RS04700 (OHM48_04700) - 947709..947876 (-) 168 WP_032499127.1 hypothetical protein -
  OHM48_RS04705 (OHM48_04705) rplL 948064..948429 (-) 366 WP_002936483.1 50S ribosomal protein L7/L12 -
  OHM48_RS04710 (OHM48_04710) rplJ 948495..948989 (-) 495 WP_002936486.1 50S ribosomal protein L10 -
  OHM48_RS04715 (OHM48_04715) topA 949566..951659 (-) 2094 WP_012775596.1 type I DNA topoisomerase -
  OHM48_RS04720 (OHM48_04720) dprA 951752..952594 (-) 843 WP_012775129.1 DNA-processing protein DprA Machinery gene
  OHM48_RS04725 (OHM48_04725) - 952653..953210 (-) 558 WP_014917244.1 sugar O-acetyltransferase -
  OHM48_RS04730 (OHM48_04730) - 953221..953481 (-) 261 WP_009909865.1 metal-sensitive transcriptional regulator -
  OHM48_RS04735 (OHM48_04735) - 953588..953911 (+) 324 WP_012775130.1 rhodanese-like domain-containing protein -
  OHM48_RS04740 (OHM48_04740) - 953908..955560 (+) 1653 WP_012775595.1 FAD-dependent oxidoreductase -
  OHM48_RS04745 (OHM48_04745) - 955668..956219 (+) 552 WP_105155705.1 DUF1836 domain-containing protein -
  OHM48_RS04750 (OHM48_04750) - 956209..956859 (+) 651 WP_105155704.1 hemolysin III family protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31246.14 Da        Isoelectric Point: 8.4451

>NTDB_id=751090 OHM48_RS04720 WP_012775129.1 951752..952594(-) (dprA) [Streptococcus suis strain ID35541]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKLKLAVVGTRNASKNGIQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=751090 OHM48_RS04720 WP_012775129.1 951752..952594(-) (dprA) [Streptococcus suis strain ID35541]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTGCGAAATGTCGCTGTAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATTAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTATCCAATCTGTTCAGAAAATTATCAAGGAATTGAGCAATCGTT
TTGTCATTGTTAGTGGTTTGGCAAGAGGAATTGATACAGCTGCCCACATCGCCAGTTTGAAAAATGGAGGCCAAACCATT
GCTGTAATCGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAAGATTTGCAGACCTATATTGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGCAATCGCATTATAGCTGGTTTGG
TGGAAGGATTGGTAGTCTGCGAGGCAAAAATGCGGTCTGGCAGCTTGATTACTTGTGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATTTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGATTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

70

100

0.7
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis SK321

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.571

100

0.636
  dprA Lactococcus lactis subsp. cremoris KW2

60

100

0.6
  dprA Legionella pneumophila strain ERS1305867

42.105

88.214

0.371
  dprA Bacillus subtilis subsp. subtilis str. 168

50.746

71.786

0.364