Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   OHM48_RS00725 Genome accession   NZ_CP109942
Coordinates   114624..115661 (+) Length   345 a.a.
NCBI ID   WP_264490838.1    Uniprot ID   -
Organism   Streptococcus suis strain ID35541     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 109624..120661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHM48_RS00710 (OHM48_00710) - 112326..112691 (+) 366 WP_024417409.1 DUF1033 family protein -
  OHM48_RS00715 (OHM48_00715) - 112726..113676 (-) 951 WP_024417410.1 S66 peptidase family protein -
  OHM48_RS00720 (OHM48_00720) comYA 113762..114712 (+) 951 WP_024417411.1 competence type IV pilus ATPase ComGA Machinery gene
  OHM48_RS00725 (OHM48_00725) comYB 114624..115661 (+) 1038 WP_264490838.1 competence type IV pilus assembly protein ComGB Machinery gene
  OHM48_RS00730 (OHM48_00730) comYC 115663..115944 (+) 282 WP_009909092.1 competence type IV pilus major pilin ComGC Machinery gene
  OHM48_RS00735 (OHM48_00735) comGD 115925..116332 (+) 408 WP_024387070.1 competence type IV pilus minor pilin ComGD -
  OHM48_RS00740 (OHM48_00740) comYE 116304..116597 (+) 294 WP_024390433.1 competence type IV pilus minor pilin ComGE Machinery gene
  OHM48_RS00745 (OHM48_00745) comGF/cglF 116584..117018 (+) 435 WP_063725150.1 competence type IV pilus minor pilin ComGF Machinery gene
  OHM48_RS00750 (OHM48_00750) comGG 116996..117406 (+) 411 WP_009909099.1 competence type IV pilus minor pilin ComGG -
  OHM48_RS00755 (OHM48_00755) comYH 117463..118416 (+) 954 WP_024409299.1 class I SAM-dependent methyltransferase Machinery gene
  OHM48_RS00760 (OHM48_00760) - 118466..119653 (+) 1188 WP_014637319.1 acetate kinase -
  OHM48_RS00765 (OHM48_00765) - 119968..120519 (+) 552 WP_024417413.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39013.09 Da        Isoelectric Point: 9.6164

>NTDB_id=751074 OHM48_RS00725 WP_264490838.1 114624..115661(+) (comYB) [Streptococcus suis strain ID35541]
MRKLIAFLQQDISVLGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADLYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLFLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVAVLAGMVWFRKTNKIKAFSRLAALPFFGKLIQIYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVQYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=751074 OHM48_RS00725 WP_264490838.1 114624..115661(+) (comYB) [Streptococcus suis strain ID35541]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCTCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCGAGTTTACTG
GCAGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TGGGTTTTCTGTTCTTGATTATGCTAGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCTGCGACCATG
CTAATTAACCATCTGCCGACTATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTGGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATCAAGGCATTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAATCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGAAGTTTGATTGGGCAAGGCTTGGATCTGCCACAGATTGTGGGCTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGGCAGAGCTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCCAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGTTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCTTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comGB/cglB Streptococcus mitis SK321

59.821

97.391

0.583
  comYB Streptococcus mutans UA140

58.651

98.841

0.58
  comYB Streptococcus mutans UA159

58.651

98.841

0.58
  comGB/cglB Streptococcus mitis NCTC 12261

59.403

97.101

0.577
  comGB/cglB Streptococcus pneumoniae Rx1

58.806

97.101

0.571
  comGB/cglB Streptococcus pneumoniae D39

58.806

97.101

0.571
  comGB/cglB Streptococcus pneumoniae R6

58.806

97.101

0.571
  comGB/cglB Streptococcus pneumoniae TIGR4

58.806

97.101

0.571
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493