Detailed information NTG0074554

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SAGCMC97051_RS05745
• Genome accession: NZ_AP020310
• Coordinates: 1080162..1081004 (-)
• Length: 280 a.a.
• NCBI ID: WP_001015240.1
• Uniprot ID: Q8DZU1
• Organism: Streptococcus agalactiae strain GCMC97051
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1075162..1086004

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAGCMC97051_RS05735 (SAGCMC97051_10560)	-	1077109..1077810 (-)	702	WP_000120355.1	ABC transporter ATP-binding protein	-
SAGCMC97051_RS05740 (SAGCMC97051_10570)	topA	1077947..1080067 (-)	2121	WP_000246611.1	type I DNA topoisomerase	-
SAGCMC97051_RS05745 (SAGCMC97051_10580)	dprA	1080162..1081004 (-)	843	WP_001015240.1	DNA-processing protein DprA	Machinery gene
SAGCMC97051_RS05750 (SAGCMC97051_10590)	-	1081142..1082170 (-)	1029	WP_000162771.1	siderophore ABC transporter substrate-binding protein	-
SAGCMC97051_RS05755 (SAGCMC97051_10600)	-	1082232..1082993 (-)	762	WP_000614752.1	ABC transporter ATP-binding protein	-
SAGCMC97051_RS05760 (SAGCMC97051_10610)	-	1082990..1083964 (-)	975	WP_000588576.1	iron chelate uptake ABC transporter family permease subunit	-
SAGCMC97051_RS05765 (SAGCMC97051_10620)	-	1083961..1084923 (-)	963	WP_000735588.1	ABC transporter permease	-
SAGCMC97051_RS05770 (SAGCMC97051_10630)	-	1085162..1085710 (-)	549	WP_000136509.1	sugar O-acetyltransferase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31294.36 Da
• Isoelectric Point: 9.3802

>NTDB_id=74554 SAGCMC97051_RS05745 WP_001015240.1 1080162..1081004(-) (dprA) [Streptococcus agalactiae strain GCMC97051]
MNHFELFKLKKAGLTNLNIHNIINYLKKNSLTSLSVRNMAVVSKCKNPTFFIENYKQLDLKKLRQEFKKFPVLSILDSNY
PLELKEIYNPPVLLFYQGNIELLSKPKLAVVGARQASQIGCQSVKKIIKETNNQFVIVSGLARGIDTAAHVSALKNGGSS
IAVIGSGLDVYYPTENKKLQEYMSYNHLVLSEYFTGEQPLKFHFPERNRIIAGLCQGIVVAEAKMRSGSLITCERALEEG
REVFAIPGNIIDGKSDGCHHLIQEGAKCIISGKDILSEYQ

Nucleotide

• Length: 843 bp

>NTDB_id=74554 SAGCMC97051_RS05745 WP_001015240.1 1080162..1081004(-) (dprA) [Streptococcus agalactiae strain GCMC97051]
ATGAATCATTTTGAACTATTTAAGCTTAAAAAAGCTGGATTAACAAATCTTAATATCCACAATATTATCAACTATCTCAA
AAAGAATAGTTTAACTTCTCTATCTGTTCGCAATATGGCCGTAGTATCAAAATGTAAAAATCCTACTTTCTTTATAGAAA
ATTATAAACAGCTAGACCTTAAAAAACTTCGACAAGAATTCAAAAAATTTCCAGTTCTATCGATTTTGGATTCTAACTAT
CCTTTAGAGTTAAAAGAAATATATAATCCACCAGTTCTACTTTTTTATCAGGGTAATATTGAACTTCTATCTAAACCTAA
ATTAGCTGTAGTGGGGGCAAGACAGGCATCTCAGATAGGTTGTCAGTCTGTTAAAAAGATTATCAAGGAGACTAACAATC
AATTTGTTATCGTAAGTGGTTTAGCGCGTGGCATTGATACAGCAGCACATGTTAGTGCTTTAAAAAATGGCGGCAGTAGT
ATAGCTGTTATCGGGAGTGGTTTAGATGTTTATTATCCAACGGAGAATAAGAAACTTCAAGAATATATGTCATATAATCA
TCTCGTATTATCAGAATATTTTACCGGAGAACAACCCTTGAAATTTCATTTCCCCGAACGTAACCGTATTATTGCAGGGC
TGTGTCAAGGTATTGTGGTTGCCGAAGCTAAGATGAGATCTGGAAGTTTAATTACCTGTGAAAGAGCATTAGAAGAGGGA
CGAGAAGTTTTTGCCATTCCCGGAAATATTATCGATGGCAAATCAGATGGATGCCACCATCTTATCCAAGAAGGAGCTAA
ATGCATTATTTCAGGAAAAGATATCCTTTCTGAATATCAGTAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-63)

3D structure

• AlphaFold DB: Q8DZU1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70.251	99.643	0.7
dprA/cilB/dalA	Streptococcus mitis SK321	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae D39	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae R6	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	61.786	100	0.618
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	61.429	100	0.614
dprA	Lactococcus lactis subsp. cremoris KW2	60.932	99.643	0.607
dprA	Latilactobacillus sakei subsp. sakei 23K	42.231	89.643	0.379