Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QBD03_RS00370 Genome accession   NZ_CP122959
Coordinates   71362..72621 (+) Length   419 a.a.
NCBI ID   WP_280102907.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain HUP1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 66362..77621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QBD03_RS00355 (QBD03_00355) yycH 68230..69561 (+) 1332 WP_011373792.1 two-component system activity regulator YycH -
  QBD03_RS00360 (QBD03_00360) - 69566..70387 (+) 822 WP_112206805.1 two-component system regulatory protein YycI -
  QBD03_RS00365 (QBD03_00365) vicX 70422..71228 (+) 807 WP_280102906.1 MBL fold metallo-hydrolase Regulator
  QBD03_RS00370 (QBD03_00370) htrA 71362..72621 (+) 1260 WP_280102907.1 trypsin-like peptidase domain-containing protein Regulator
  QBD03_RS00375 (QBD03_00375) rlmH 73166..73645 (+) 480 WP_011373797.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  QBD03_RS00380 (QBD03_00380) - 73835..74119 (+) 285 WP_280102908.1 Mor transcription activator family protein -
  QBD03_RS00385 (QBD03_00385) - 74148..74882 (+) 735 WP_280102909.1 zinc ribbon domain-containing protein -
  QBD03_RS00390 (QBD03_00390) - 74963..75433 (+) 471 WP_280102910.1 hypothetical protein -
  QBD03_RS00395 (QBD03_00395) - 75514..75783 (+) 270 WP_280102911.1 hypothetical protein -
  QBD03_RS00400 (QBD03_00400) - 75859..76356 (+) 498 WP_280102912.1 DUF1643 domain-containing protein -
  QBD03_RS00405 (QBD03_00405) - 76362..77117 (+) 756 WP_280102913.1 hypothetical protein -
  QBD03_RS00410 (QBD03_00410) - 77231..77485 (+) 255 WP_280102914.1 hypothetical protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 42726.86 Da        Isoelectric Point: 9.4566

>NTDB_id=744593 QBD03_RS00370 WP_280102907.1 71362..72621(+) (htrA) [Latilactobacillus sakei strain HUP1]
MNQNSGLMKTAVVAVISALIGGGAAYAGFSRLGSSANDVTTATQTPTKAGATKISNIKVNSSSQTTTAFQKVNTSVVSVV
NLQKQQQSTGDLSSLFGSGSTNSNSSSSKSSSSDLEESSEGSGLIYEKKDGKAYIVTNNHVVAGSDKIEVILSDGTKLEA
SLVGTDAVSDLAVLKINGTKVKKTATFGDSDSIKAGESVLAIGSPLGSEYATSVTQGIISAKKRTIDVTDETTGQTTGQA
TVIQTDTAINPGNSGGPLVNMAGQVVGINSMKLASNGDTTVEGMGFAIPSNEVVKIINQLVANGKVVRPALGISVIDLTN
ISSTQQSSVLKLPSTVNSGVVVASVTSNSVAKKVGISKYDVIVGLGGKTVSSVADLHTILYSYAMNSTTEIQYYHNGSLK
KANVKLTQAASSDSTTTTK

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=744593 QBD03_RS00370 WP_280102907.1 71362..72621(+) (htrA) [Latilactobacillus sakei strain HUP1]
ATGAATCAAAATTCAGGATTAATGAAAACAGCGGTTGTTGCAGTTATTTCAGCATTGATTGGTGGGGGCGCAGCCTATGC
CGGTTTTTCTCGACTCGGCAGTTCGGCCAATGATGTCACGACTGCAACGCAGACGCCTACTAAAGCGGGGGCAACTAAGA
TTAGTAATATCAAAGTGAACTCATCATCACAGACGACAACAGCCTTCCAAAAGGTTAATACATCAGTTGTATCCGTTGTG
AACTTACAAAAACAACAACAATCAACCGGTGACCTGAGTTCATTATTTGGTTCAGGCAGCACCAACAGCAATAGTAGTTC
TTCTAAGAGCAGTAGCAGTGATTTAGAAGAATCCAGTGAAGGTTCAGGTTTAATCTACGAGAAAAAAGACGGCAAAGCTT
ACATCGTGACGAATAATCACGTGGTTGCTGGTTCTGATAAAATCGAAGTCATTTTGAGTGATGGCACAAAATTGGAAGCT
AGTTTAGTTGGGACAGATGCTGTTTCTGATTTGGCTGTCTTAAAAATTAACGGGACTAAAGTGAAGAAGACGGCAACGTT
TGGTGATTCAGATAGTATCAAAGCTGGTGAATCAGTTCTTGCGATCGGCTCACCATTGGGTTCAGAATACGCAACTTCTG
TCACACAAGGGATCATTTCTGCTAAGAAACGGACAATTGATGTGACGGACGAAACAACCGGCCAAACAACTGGTCAAGCG
ACTGTTATTCAAACTGATACAGCGATTAACCCTGGGAACTCAGGTGGCCCATTAGTTAATATGGCCGGTCAAGTTGTTGG
GATTAATTCAATGAAGTTAGCCTCAAATGGTGATACGACAGTTGAAGGGATGGGCTTTGCTATTCCAAGTAACGAAGTTG
TTAAAATTATTAATCAATTAGTGGCTAACGGGAAAGTCGTTAGACCAGCACTTGGGATTAGTGTGATAGATTTAACCAAT
ATTTCATCAACACAACAATCTTCAGTATTAAAACTACCATCAACCGTCAATAGCGGGGTAGTGGTTGCCTCAGTAACAAG
CAATTCAGTTGCTAAGAAAGTTGGGATTAGTAAATACGATGTGATTGTCGGTTTAGGCGGCAAGACGGTTTCAAGCGTTG
CAGACTTACACACAATCCTATACAGTTATGCGATGAATAGTACAACTGAAATTCAGTACTACCATAATGGCAGCTTGAAA
AAAGCGAATGTTAAACTCACACAAGCAGCTTCATCAGATAGTACGACAACAACTAAATAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(309-406)

Trypsin-like peptidase domain (Trypsin_2)

(121-268)

Peptidase family M50 (Peptidase_M50)

(284-413)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

45.209

97.136

0.439
  htrA Streptococcus gordonii str. Challis substr. CH1

42.512

98.807

0.42
  htrA Streptococcus mutans UA159

46.237

88.783

0.411
  htrA Streptococcus pneumoniae TIGR4

48.424

83.294

0.403
  htrA Streptococcus pneumoniae R6

48.424

83.294

0.403
  htrA Streptococcus pneumoniae Rx1

48.424

83.294

0.403
  htrA Streptococcus pneumoniae D39

48.424

83.294

0.403