Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FNL60_RS00355 Genome accession   NZ_AP019720
Coordinates   57134..58048 (+) Length   304 a.a.
NCBI ID   WP_002280105.1    Uniprot ID   -
Organism   Streptococcus mutans strain NBRC 13955     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 52134..63048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNL60_RS00330 (SM3g_00430) - 52578..52997 (+) 420 WP_002280110.1 SRPBCC family protein -
  FNL60_RS00335 (SM3g_00440) - 53101..53697 (+) 597 WP_002280109.1 hypothetical protein -
  FNL60_RS00340 (SM3g_00450) - 53719..54450 (+) 732 WP_002280108.1 hypothetical protein -
  FNL60_RS00345 (SM3g_00460) purB 54744..56042 (+) 1299 WP_002280107.1 adenylosuccinate lyase -
  FNL60_RS00350 (SM3g_00470) - 56062..56748 (+) 687 WP_002280106.1 DNA alkylation repair protein -
  FNL60_RS00355 (SM3g_00480) comR 57134..58048 (+) 915 WP_002280105.1 helix-turn-helix domain-containing protein Regulator
  FNL60_RS00360 (SM3g_00490) - 58580..60424 (-) 1845 WP_002280104.1 carbohydrate-binding domain-containing protein -
  FNL60_RS00365 (SM3g_00500) - 60922..61197 (+) 276 WP_002270796.1 hypothetical protein -
  FNL60_RS00370 (SM3g_00510) - 61293..62915 (+) 1623 WP_002280103.1 class I SAM-dependent DNA methyltransferase -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 35304.52 Da        Isoelectric Point: 5.1281

>NTDB_id=73492 FNL60_RS00355 WP_002280105.1 57134..58048(+) (comR) [Streptococcus mutans strain NBRC 13955]
MLKDFGKKIKSLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSMPTLNKAIYIVGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLTEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide


Download         Length: 915 bp        

>NTDB_id=73492 FNL60_RS00355 WP_002280105.1 57134..58048(+) (comR) [Streptococcus mutans strain NBRC 13955]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAGCCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCTTGATGA
ATCGCAGTTGTCAACACGGCAGCTGACTAGAATTGAATCAGGACAGTCTATGCCAACTCTTAATAAAGCTATTTATATTG
TAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAAAATGTCGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGTGACCAACAAAGATTAACTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTTTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTTAGCAATAAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(9-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

98.026

100

0.98
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.431

94.737

0.497
  comR Streptococcus pyogenes MGAS8232

47.02

99.342

0.467
  comR Streptococcus pyogenes MGAS315

47.157

98.355

0.464
  comR Streptococcus suis P1/7

43.144

98.355

0.424
  comR Streptococcus suis 05ZYH33

43.144

98.355

0.424
  comR Streptococcus suis D9

36.667

98.684

0.362

Multiple sequence alignment