Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   P5661_RS22025 Genome accession   NZ_CP120600
Coordinates   4186879..4188081 (-) Length   400 a.a.
NCBI ID   WP_021481077.1    Uniprot ID   -
Organism   Bacillus subtilis strain PRO112     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4181879..4193081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5661_RS22000 (P5661_22000) rocE 4181991..4183394 (-) 1404 WP_014481465.1 amino acid permease -
  P5661_RS22005 (P5661_22005) rocD 4183617..4184822 (-) 1206 WP_024571526.1 ornithine aminotransferase -
  P5661_RS22010 (P5661_22010) rocR 4185060..4186445 (+) 1386 WP_277709185.1 arginine utilization regulatory protein RocR -
  P5661_RS22015 (P5661_22015) - 4186427..4186615 (-) 189 Protein_4280 ATP-binding protein -
  P5661_RS22020 (P5661_22020) - 4186732..4186859 (-) 128 Protein_4281 hypothetical protein -
  P5661_RS22025 (P5661_22025) htrA 4186879..4188081 (-) 1203 WP_021481077.1 serine protease HtrC Regulator
  P5661_RS22030 (P5661_22030) vicX 4188163..4188957 (-) 795 WP_003242676.1 MBL fold metallo-hydrolase Regulator
  P5661_RS22035 (P5661_22035) walI 4188979..4189821 (-) 843 WP_064671690.1 WalRK two-component regulatory system regulator WalI -
  P5661_RS22040 (P5661_22040) walH 4189808..4191175 (-) 1368 WP_072175742.1 WalRK two-component regulatory system regulator WalH -
  P5661_RS22045 (P5661_22045) walK 4191165..4193000 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.3354

>NTDB_id=733048 P5661_RS22025 WP_021481077.1 4186879..4188081(-) (htrA) [Bacillus subtilis strain PRO112]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=733048 P5661_RS22025 WP_021481077.1 4186879..4188081(-) (htrA) [Bacillus subtilis strain PRO112]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATTCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(185-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.542

100

0.417
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373