Detailed information NTG0072880

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: C11O2_RS04545
• Genome accession: NZ_AP019548
• Coordinates: 873069..873905 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 10-85
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 868069..878905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C11O2_RS04515 (A85_08090)	-	868623..868991 (+)	369	WP_010922310.1	hypothetical protein	-
C11O2_RS04520 (A85_08100)	-	869041..869952 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
C11O2_RS04525 (A85_08110)	trhA	870069..870719 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
C11O2_RS04530 (A85_08120)	-	870716..871156 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
C11O2_RS04535 (A85_08130)	ylqF	871375..872223 (+)	849	WP_061114967.1	ribosome biogenesis GTPase YlqF	-
C11O2_RS04540 (A85_08140)	-	872213..873004 (+)	792	WP_011285534.1	ribonuclease HII	-
C11O2_RS04545 (A85_08150)	dprA	873069..873905 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
C11O2_RS04550 (A85_08160)	topA	874012..876141 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
C11O2_RS09045	-	876216..877098 (-)	883	Protein_821	LysR family transcriptional regulator	-
C11O2_RS04565 (A85_08180)	-	877111..877656 (+)	546	Protein_822	PTS sugar transporter subunit IIC	-
C11O2_RS04570 (A85_08190)	-	877671..878663 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=72880 C11O2_RS04545 WP_010922314.1 873069..873905(+) (dprA) [Streptococcus pyogenes strain 10-85]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=72880 C11O2_RS04545 WP_010922314.1 873069..873905(+) (dprA) [Streptococcus pyogenes strain 10-85]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367