Detailed information NTG0072138

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: EL334_RS06530
• Genome accession: NZ_AP019192
• Coordinates: 1230095..1230943 (-)
• Length: 282 a.a.
• NCBI ID: WP_033705344.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ASP0581
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1225095..1235943

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL334_RS06515 (ASP0581_12240)	-	1225379..1225738 (-)	360	WP_001220357.1	YbaN family protein	-
EL334_RS06520 (ASP0581_12250)	topA	1225959..1228046 (-)	2088	WP_000179635.1	type I DNA topoisomerase	-
EL334_RS06525 (ASP0581_12260)	-	1228213..1229256 (-)	1044	WP_001812957.1	TIGR00341 family protein	-
EL334_RS06530 (ASP0581_12270)	dprA/cilB/dalA	1230095..1230943 (-)	849	WP_033705344.1	DNA-processing protein DprA	Machinery gene
EL334_RS06535 (ASP0581_12280)	-	1231039..1231728 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
EL334_RS06540 (ASP0581_12290)	-	1231740..1232618 (-)	879	WP_000837609.1	DMT family transporter	-
EL334_RS06545 (ASP0581_12300)	licA	1232608..1233477 (-)	870	WP_033705343.1	choline kinase LicA	-
EL334_RS06550 (ASP0581_12310)	-	1233494..1234516 (-)	1023	WP_000609885.1	ribitol-5-phosphate dehydrogenase	-
EL334_RS06555 (ASP0581_12320)	-	1234521..1235228 (-)	708	WP_033705342.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31120.76 Da
• Isoelectric Point: 5.2061

>NTDB_id=72138 EL334_RS06530 WP_033705344.1 1230095..1230943(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain ASP0581]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=72138 EL334_RS06530 WP_033705344.1 1230095..1230943(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain ASP0581]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGATAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.456	100	0.376