Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   NWO26_RS03060 Genome accession   NZ_CP102797
Coordinates   601661..602368 (-) Length   235 a.a.
NCBI ID   WP_011681206.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST057-1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 596661..607368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWO26_RS03035 yidA 597012..597821 (+) 810 WP_011226081.1 sugar-phosphatase -
  NWO26_RS03040 - 597823..599037 (+) 1215 WP_004197368.1 aminoacyltransferase -
  NWO26_RS03045 - 599089..599450 (-) 362 Protein_600 YbaN family protein -
  NWO26_RS03050 vicX 599510..600322 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  NWO26_RS03055 vicK 600328..601668 (-) 1341 WP_011681205.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NWO26_RS03060 vicR 601661..602368 (-) 708 WP_011681206.1 response regulator YycF Regulator
  NWO26_RS03065 - 602895..603662 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  NWO26_RS03070 - 603674..604507 (+) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  NWO26_RS03075 - 604525..605223 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  NWO26_RS03080 - 605235..605885 (+) 651 WP_014608375.1 amino acid ABC transporter permease -
  NWO26_RS03085 endA 605957..606838 (-) 882 WP_011681210.1 DNA/RNA non-specific endonuclease Machinery gene
  NWO26_RS03090 - 606900..607088 (-) 189 WP_011226090.1 DNA-directed RNA polymerase subunit beta -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27058.98 Da        Isoelectric Point: 5.0130

>NTDB_id=719011 NWO26_RS03060 WP_011681206.1 601661..602368(-) (vicR) [Streptococcus thermophilus strain ST057-1]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=719011 NWO26_RS03060 WP_011681206.1 601661..602368(-) (vicR) [Streptococcus thermophilus strain ST057-1]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.32

98.298

0.455
  covR Streptococcus salivarius strain HSISS4

45.299

99.574

0.451
  scnR Streptococcus mutans UA159

38.559

100

0.387