Detailed information NTG0719008

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NWO26_RS02155
• Genome accession: NZ_CP102797
• Coordinates: 419382..420221 (+)
• Length: 279 a.a.
• NCBI ID: WP_011225887.1
• Uniprot ID: Q5M4N4
• Organism: Streptococcus thermophilus strain ST057-1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 414382..425221

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWO26_RS02125	-	414798..415325 (+)	528	WP_011681081.1	ECF transporter S component	-
NWO26_RS02130	-	415349..415864 (+)	516	WP_014621521.1	transcription repressor NadR	-
NWO26_RS02135	-	415959..416648 (+)	690	WP_113870366.1	XRE family transcriptional regulator	-
NWO26_RS02140	ylqF	416776..417630 (+)	855	WP_113870365.1	ribosome biogenesis GTPase YlqF	-
NWO26_RS02145	-	417617..418384 (+)	768	WP_064355754.1	ribonuclease HII	-
NWO26_RS02150	-	418395..419315 (+)	921	WP_014608255.1	ROK family protein	-
NWO26_RS02155	dprA	419382..420221 (+)	840	WP_011225887.1	DNA-processing protein DprA	Machinery gene
NWO26_RS02160	topA	420389..422533 (+)	2145	WP_011681086.1	type I DNA topoisomerase	-
NWO26_RS02165	-	422650..423474 (+)	825	WP_011681087.1	TraX family protein	-
NWO26_RS02170	-	423510..424169 (+)	660	WP_011227158.1	response regulator transcription factor	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31247.18 Da
• Isoelectric Point: 8.6571

>NTDB_id=719008 NWO26_RS02155 WP_011225887.1 419382..420221(+) (dprA) [Streptococcus thermophilus strain ST057-1]
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAVLFMEKYKNLDVKQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVHELGNAFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHYPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDIISEFS

Nucleotide

• Length: 840 bp

>NTDB_id=719008 NWO26_RS02155 WP_011225887.1 419382..420221(+) (dprA) [Streptococcus thermophilus strain ST057-1]
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTAACGAATTTAAACATCCTTAACATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCCGTTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAAGCAGCTTAAGGAAGATTTTCAACGTTTTCCGACCTTATCAATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTCCTCCTCTTTTATCAAGGGAATATTGATTTGCTAAGTAAACCCAAGTT
AGCGGTAGTTGGTGCCAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTTCGAAAAATTGTTCATGAACTTGGGAATGCCT
TTACTATTGTAAGTGGCTTGGCGCGTGGAATTGATACTTGTGCTCATATGGAGGCCTTAAAAAATAAAGGTAACACCATT
GCAGTTATCGGGACTGGGCTAGACGTATATTATCCTAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTACAGAATACGGACCGGGTGAACAGCCACTTAAATACCATTATCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGGGTTATGGTGGTTGAAGCCAAGCTTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGAAGA
GATGTTTTCGCCATACCAGGAAATATTTTAGATGGAAAATCGGATGGATGCCATCACCTCATTCAAGAGGGCGCAAAGTG
CATTACTACAGGATTTGACATCATTTCAGAATTTTCATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: Q5M4N4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	72.043	100	0.72
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus mitis SK321	62.95	99.642	0.627
dprA	Lactococcus lactis subsp. cremoris KW2	60.432	99.642	0.602
dprA	Latilactobacillus sakei subsp. sakei 23K	39.768	92.832	0.369
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75.269	0.362