Detailed information NTG0718724

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: NWE22_RS10295
• Genome accession: NZ_CP102747
• Coordinates: 2013195..2014376 (+)
• Length: 393 a.a.
• NCBI ID: WP_171989296.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain SFJ45
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2008195..2019376

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE22_RS10265 (NWE22_10265)	-	2008825..2011404 (+)	2580	WP_239604378.1	YfhO family protein	-
NWE22_RS10285 (NWE22_10285)	-	2011833..2012495 (-)	663	WP_239604379.1	YoaK family protein	-
NWE22_RS10290 (NWE22_10290)	rlmH	2012523..2013002 (-)	480	WP_239604380.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
NWE22_RS10295 (NWE22_10295)	htrA	2013195..2014376 (+)	1182	WP_171989296.1	trypsin-like peptidase domain-containing protein	Regulator
NWE22_RS10300 (NWE22_10300)	spo0J	2014439..2015197 (+)	759	WP_239604381.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 393 a.a.
• Molecular weight: 41154.80 Da
• Isoelectric Point: 4.2375

>NTDB_id=718724 NWE22_RS10295 WP_171989296.1 2013195..2014376(+) (htrA) [Streptococcus parasuis strain SFJ45]
MKKLLKFVILFVVGFLGGIGGYYFASSTLTQGNSTSNQANTTSVSNVQYTNDTSTTQAVEKVQDAVVSVINYQTQSSNSL
SSIFGNIESSDELAVAGEGSGVIYKKDGDTAYIVTNNHVISGAEKIDILLASGEKLSGELVGADTYSDIAVIKIAADKVT
TIAEFANSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQTEDGQTISTNAIQTDTAINPGNSGGPLINIQGQ
VIGINSSKITSSSVSSSGVAVEGMGFAIPSNDTVQIINQLETNGKVTRPALGVQMVNLTDLSTSQLEKAGLANTDLTSGV
LIVSTQSGLPADGKFEPYDVIIEIDGETIENKSDLQSELYKHQIGDTITVTYYRNNKKMTVDIKLTHSTDDLS

Nucleotide

• Length: 1182 bp

>NTDB_id=718724 NWE22_RS10295 WP_171989296.1 2013195..2014376(+) (htrA) [Streptococcus parasuis strain SFJ45]
ATGAAAAAATTATTGAAATTTGTTATTTTGTTTGTTGTTGGATTTTTAGGAGGAATTGGTGGGTATTACTTTGCTTCATC
AACTCTGACTCAAGGAAATTCTACTTCAAATCAAGCAAATACAACCAGTGTGAGCAATGTTCAATATACCAACGATACTT
CCACCACTCAAGCTGTGGAAAAAGTTCAAGATGCTGTTGTCTCCGTTATCAATTATCAAACTCAATCATCGAATAGCCTC
AGTTCTATTTTTGGCAACATTGAAAGTTCAGATGAGCTAGCTGTTGCTGGAGAAGGTTCAGGTGTTATTTATAAAAAAGA
TGGTGATACAGCATATATTGTTACAAACAACCACGTAATTTCAGGTGCTGAAAAAATCGATATACTTTTGGCTTCTGGAG
AAAAGCTTAGCGGAGAACTCGTAGGTGCAGATACTTATTCAGACATTGCTGTTATCAAAATTGCTGCAGATAAAGTGACC
ACTATTGCTGAATTTGCTAATTCAGACACAATTAAAGTTGGAGAAACTGCGATTGCAATTGGTAGCCCATTAGGAAGTGT
CTATGCAAATACAGTAACTCAGGGGATTATTTCTAGTCTCAGTCGTACAGTAACTTCACAAACAGAAGATGGCCAAACAA
TCTCAACAAATGCTATCCAGACTGATACAGCCATTAACCCAGGTAACTCAGGTGGACCACTTATCAATATTCAAGGACAA
GTTATCGGTATCAACTCAAGTAAAATAACCTCTAGTTCTGTCAGCAGTTCAGGAGTTGCAGTAGAAGGAATGGGCTTTGC
AATTCCCTCAAATGATACTGTACAGATAATTAATCAATTAGAAACAAATGGTAAAGTTACTCGTCCAGCTCTTGGCGTAC
AAATGGTCAATCTAACAGACCTATCTACTAGTCAATTAGAAAAAGCAGGATTAGCAAATACAGACTTAACATCTGGAGTA
CTAATTGTATCTACTCAATCAGGTTTGCCAGCTGATGGAAAATTTGAACCATATGATGTCATTATTGAAATCGATGGTGA
AACCATTGAAAATAAGAGTGATTTACAAAGTGAACTTTACAAGCATCAAATTGGCGACACCATAACTGTTACCTATTATA
GAAATAATAAGAAAATGACTGTTGACATTAAGTTGACACATTCAACGGATGATTTGTCATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (289-385)

• Trypsin-like peptidase domain (Trypsin_2) (99-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.266	100	0.616
htrA	Streptococcus gordonii str. Challis substr. CH1	59.898	100	0.601
htrA	Streptococcus pneumoniae Rx1	58.418	99.746	0.583
htrA	Streptococcus pneumoniae TIGR4	58.418	99.746	0.583
htrA	Streptococcus pneumoniae D39	58.418	99.746	0.583
htrA	Streptococcus pneumoniae R6	58.418	99.746	0.583
htrA	Streptococcus mitis NCTC 12261	57.908	99.746	0.578