Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   NWE22_RS04865 Genome accession   NZ_CP102747
Coordinates   955328..955999 (+) Length   223 a.a.
NCBI ID   WP_277745712.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SFJ45     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 950328..960999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS04855 (NWE22_04855) - 952215..953153 (+) 939 WP_277745710.1 DPM/DPG synthase family glycosyltransferase -
  NWE22_RS04860 (NWE22_04860) - 953290..955149 (+) 1860 WP_277745711.1 hypothetical protein -
  NWE22_RS04865 (NWE22_04865) ciaR 955328..955999 (+) 672 WP_277745712.1 response regulator transcription factor Regulator
  NWE22_RS04870 (NWE22_04870) ciaH 955992..957365 (+) 1374 WP_277745713.1 HAMP domain-containing sensor histidine kinase Regulator
  NWE22_RS04875 (NWE22_04875) - 957453..958670 (+) 1218 WP_277745714.1 transglutaminase domain-containing protein -
  NWE22_RS04880 (NWE22_04880) rpsT 958704..958952 (-) 249 WP_171988421.1 30S ribosomal protein S20 -
  NWE22_RS04885 (NWE22_04885) coaA 959011..959931 (-) 921 WP_237396439.1 type I pantothenate kinase -
  NWE22_RS04890 (NWE22_04890) - 960007..960597 (+) 591 WP_277745715.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25212.84 Da        Isoelectric Point: 4.2459

>NTDB_id=718695 NWE22_RS04865 WP_277745712.1 955328..955999(+) (ciaR) [Streptococcus parasuis strain SFJ45]
MIKILLIEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVSTPVLITTA
KEGLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNTTTVNGQEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGENLQTLRSVGYILKNV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=718695 NWE22_RS04865 WP_277745712.1 955328..955999(+) (ciaR) [Streptococcus parasuis strain SFJ45]
ATGATAAAAATATTATTGATCGAAGACGATTTAAGCCTTTCTAATTCAGTCTTTGATTTTTTAGATGATTTTGCAGACGT
TATGCAAGTTTTTGATGGTGAAGAAGGTATTTACGAAGCGGAAACAGGGGTTTATGACTTAATTCTCTTAGATTTAATGT
TACCTGAGAAAGATGGTTTTCAAGTATTAAAAGAATTGCGTGAAAAAGGGGTCTCAACTCCCGTTCTGATTACGACAGCC
AAGGAAGGCCTAGAGGATAAAGGACATGGGTTTGAATTGGGTGCAGATGACTATCTCACAAAACCATTCTATTTAGAAGA
ACTCAAAATGCGTATTCAAGCCTTGTTAAAACGAGCAGGGAAGTTCAATGAAAATACTCTAACATACGGAGATGTTACTG
TCGACTTATCTACAAATACTACGACAGTCAATGGTCAAGAAGTAGAATTGTTAGGGAAAGAGTTCGATTTGTTGGTATAT
TTCTTACAAAACCAGAATGTAATTTTACCTAAAACACAGATTTTTGATCGTATTTGGGGATTTGATAGTGATACAACCAT
TTCAGTTGTTGAAGTTTACGTATCAAAAGTAAGGAAAAAATTGAAAGGAACCGCATTTGGAGAAAATCTTCAAACTCTTC
GTAGTGTCGGTTACATTTTGAAAAATGTCTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

88.789

100

0.888
  ciaR Streptococcus pneumoniae Rx1

88.341

100

0.883
  ciaR Streptococcus pneumoniae D39

88.341

100

0.883
  ciaR Streptococcus pneumoniae R6

88.341

100

0.883
  ciaR Streptococcus pneumoniae TIGR4

88.341

100

0.883
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.053

100

0.386
  vicR Streptococcus mutans UA159

34.615

100

0.363