Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NWE22_RS04870 Genome accession   NZ_CP102747
Coordinates   955992..957365 (+) Length   457 a.a.
NCBI ID   WP_277745713.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SFJ45     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 950992..962365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS04855 (NWE22_04855) - 952215..953153 (+) 939 WP_277745710.1 DPM/DPG synthase family glycosyltransferase -
  NWE22_RS04860 (NWE22_04860) - 953290..955149 (+) 1860 WP_277745711.1 hypothetical protein -
  NWE22_RS04865 (NWE22_04865) ciaR 955328..955999 (+) 672 WP_277745712.1 response regulator transcription factor Regulator
  NWE22_RS04870 (NWE22_04870) ciaH 955992..957365 (+) 1374 WP_277745713.1 HAMP domain-containing sensor histidine kinase Regulator
  NWE22_RS04875 (NWE22_04875) - 957453..958670 (+) 1218 WP_277745714.1 transglutaminase domain-containing protein -
  NWE22_RS04880 (NWE22_04880) rpsT 958704..958952 (-) 249 WP_171988421.1 30S ribosomal protein S20 -
  NWE22_RS04885 (NWE22_04885) coaA 959011..959931 (-) 921 WP_237396439.1 type I pantothenate kinase -
  NWE22_RS04890 (NWE22_04890) - 960007..960597 (+) 591 WP_277745715.1 class I SAM-dependent methyltransferase -
  NWE22_RS04895 (NWE22_04895) - 960594..961871 (+) 1278 WP_277745716.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 51466.56 Da        Isoelectric Point: 4.9433

>NTDB_id=718696 NWE22_RS04870 WP_277745713.1 955992..957365(+) (ciaH) [Streptococcus parasuis strain SFJ45]
MSKRFKKIISTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTSDSTLARIKDAPALVVGFAIARTYEPNSEFIIQD
GNIADESDSAESNSDTPNSPKNQKDDQLKLGYNTHVLLYSNDGVVVNPDNFTGLSDLSLDKKNIGEIKEATVDSTFGGSE
DYRYVTIELEPDDLGYYSSYDIKYATIFVNVSQIKSSIETYETAVAIVMVSAWLISILASIYLSNLSMRPILISYQKQKD
FVENASHELRTPLAVLQNRLEGLFRHPNATILESSESIGSSLEEVRNMRMLTTNLLNLARRDDGFKLDIVEVPPSYFDEI
FENYMMIADENGKTVTVNNLIDQPIRTDKVLVKQLLTILFDNAMKYTEEDGAIQVTANIKDKLVYFTVADNGLGISDSDK
KKIFDRFYRVDKARTRSKGGFGLGLSLALQISNSLKGTITVRDNQPKGTIFEVRLPR

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=718696 NWE22_RS04870 WP_277745713.1 955992..957365(+) (ciaH) [Streptococcus parasuis strain SFJ45]
ATGTCTAAGCGATTTAAAAAAATCATTTCAACAGATAAATTTTCATTTTTTATCAGATATTTTGCTGTTTTTACACTCAT
TTTCGGATTAATGACCGCCATTATCTTCCAGTTAATGCGCTCAACTATGTATCAGACTTCTGATTCAACACTGGCTCGTA
TCAAAGATGCCCCTGCTTTGGTGGTTGGTTTTGCCATTGCACGGACCTATGAACCAAATTCAGAATTCATTATTCAAGAT
GGAAATATTGCTGATGAAAGTGATTCTGCAGAATCTAATTCAGATACACCAAACTCCCCTAAAAATCAGAAAGACGATCA
GTTGAAACTTGGTTACAATACACATGTATTACTCTATTCAAATGATGGTGTAGTCGTTAATCCAGATAACTTTACAGGAC
TTTCTGATTTATCCTTAGACAAGAAAAATATAGGCGAAATAAAGGAAGCAACGGTTGATTCTACATTCGGGGGTTCAGAA
GATTATCGTTATGTTACTATTGAATTGGAGCCAGATGACCTTGGCTATTATTCTTCCTATGATATTAAATACGCGACAAT
TTTCGTGAATGTGAGTCAGATAAAATCATCCATTGAGACGTATGAAACTGCTGTAGCTATTGTCATGGTATCTGCTTGGC
TTATTTCCATCTTGGCTAGTATTTATCTGTCAAATTTGAGTATGCGACCTATCTTAATTAGCTATCAAAAACAAAAGGAT
TTCGTTGAGAATGCTAGTCATGAATTGAGAACGCCTTTAGCTGTGTTACAGAATCGTTTGGAAGGTCTTTTTAGACATCC
AAATGCAACCATTTTGGAAAGTAGTGAGAGTATAGGATCAAGCCTAGAGGAAGTACGTAATATGCGTATGTTAACTACGA
ATTTACTGAATTTAGCTCGTCGAGATGATGGTTTCAAATTAGATATAGTTGAAGTCCCACCTAGCTATTTTGATGAAATC
TTTGAGAATTACATGATGATTGCAGATGAAAATGGTAAAACAGTCACGGTTAATAATTTGATTGATCAACCAATTCGGAC
GGATAAGGTGTTGGTAAAACAGCTTCTAACCATCCTATTTGATAATGCAATGAAGTATACCGAAGAAGATGGCGCTATAC
AAGTGACAGCCAATATCAAAGATAAGTTAGTTTACTTTACGGTAGCAGACAATGGATTGGGTATCAGTGATAGCGATAAA
AAGAAAATTTTTGATCGATTTTATCGTGTAGACAAGGCCCGTACTCGGAGCAAGGGTGGGTTTGGTCTCGGTTTATCCTT
AGCCTTACAAATTTCCAATAGTTTGAAAGGCACAATCACTGTGCGGGATAATCAGCCTAAAGGAACTATTTTTGAGGTAA
GATTGCCGAGATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(238-304)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-456)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50.658

99.781

0.505
  ciaH Streptococcus pneumoniae D39

50.658

99.781

0.505
  ciaH Streptococcus pneumoniae R6

50.658

99.781

0.505
  ciaH Streptococcus pneumoniae TIGR4

50.658

99.781

0.505
  ciaH Streptococcus mutans UA159

50.11

99.125

0.497